CIS 2,CIS-2,CIS2,Cish 2,Cish2,Cytokine inducible SH2 protein 2,Cytokine-inducible SH2 protein 2,SOCS 2,SOCS-2,Socs2,SOCS2,SSI 2,SSI-2,SSI2,STAT induced STAT inhibitor 2,STAT-induced STAT inhibitor 2,STATI 2,STATI2,Suppressor of cytokine signaling 2
Purification
Affinity purification
Immunogen
Synthesized peptide derived from the Internal region of human SOCS-2.
SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. SOCS2 appears to be a negative regulator in the growth hormone/IGF1 signaling pathway. Probable substrate recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.