IGSF8 antibody

Catalog No. ABIN5957935

Product Details anti-IGSF8 Antibody

Target: IGSF8 (Immunoglobulin Superfamily, Member 8 (IGSF8))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IGSF8 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Specificity: CD316,CD316 antigen,CD81 partner 3,CD81P3,EWI-2,EWI2,Glu-Trp-Ile EWI motif-containing protein 2,igsf-8,IgSF8,IGSF8,Immunoglobulin superfamily member 8,Immunoglobulin superfamily member 8 precursor,KCT-4,KCT4,Keratinocytes-associated transmembrane protein 4,LIR-D1,PGRL,Prostaglandin regulatory-like protein

Purification: Affinity purification

Immunogen: Synthesized peptide derived from the Internal region of human CD316.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, ELISA 1:20000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol,  pH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for IGSF8

Target: IGSF8 (Immunoglobulin Superfamily, Member 8 (IGSF8))

Alternative Name: CD316 (IGSF8 Products)

Synonyms: MGC77222 antibody, IGSF8 antibody, MGC151661 antibody, CD316 antibody, CD81P3 antibody, EWI-2 antibody, EWI2 antibody, KCT-4 antibody, LIR-D1 antibody, PGRL antibody, AA033172 antibody, AU041109 antibody, ESTM34 antibody, R75384 antibody, immunoglobulin superfamily, member 8 antibody, immunoglobulin superfamily member 8 antibody, igsf8 antibody, IGSF8 antibody, Igsf8 antibody

Background: May play a key role in diverse functions ascribed to CD81 and CD9 such as oocytes fertilization or hepatitis C virus function. May regulate proliferation and differentiation of keratinocytes. May be a negative regulator of cell motility: suppresses T-cell mobility coordinately with CD81, associates with CD82 to suppress prostate cancer cell migration, regulates epidermoid cell reaggregation and motility on laminin-5 with CD9 and CD81 as key linkers. May also play a role on integrin-dependent morphology and motility functions. May participate in the regulation of neurite outgrowth and maintenance of the neural network in the adult brain.

Molecular Weight: 65kDa

Gene ID: 93185

UniProt: Q969P0