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Survivin antibody
BIRC5
Reactivity: Human, Rat
WB, IHC (p)
Host: Mouse
Monoclonal
4E2
unconjugated
Product Details anti-Survivin Antibody
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Target
See all Survivin (BIRC5) Antibodies
Survivin (BIRC5)
(Baculoviral IAP Repeat-Containing 5 (BIRC5))
Reactivity
All reactivities for Survivin antibodies
Human, Rat
Host
All hosts for Survivin antibodies
Mouse
Clonality
All clonalities for Survivin antibodies
Monoclonal
Conjugate
All conjugates for Survivin antibodies
This Survivin antibody is un-conjugated
Application
All applications for Survivin antibodies
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Specificity
API4,Apoptosis inhibitor 4,Apoptosis inhibitor survivin,Apoptosis inhibitor4,Baculoviral IAP repeat containing 5,Baculoviral IAP repeat containing protein 5,Baculoviral IAP repeat-containing protein 5,BIRC 5,BIRC5,BIRC5,EPR 1,IAP4,Survivin variant 3 alpha,SVV,TIAP
Purification
Protein A purification
Immunogen
Recombinant Protein
Clone
4E2
Isotype
IgG
Top Product
Discover our top product BIRC5 Primary Antibody
Alternatives
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Application Details
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Application Notes
WB 1:1000-2000, IHC 1:50-1:200
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
1 mg/mL
Buffer
PBS with 0.02 % sodium azide and 50 % glycerol pH 7.4.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Store at -20°C. Avoid freeze / thaw cycles.
Target Details for Survivin
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Target
Survivin (BIRC5)
(Baculoviral IAP Repeat-Containing 5 (BIRC5))
Alternative Name
Survivin (BIRC5 Products )
Synonyms
AP14 antibody, API4 antibody, EPR-1 antibody, AAC-11 antibody, Api4 antibody, TIAP antibody, survivin40 antibody, bir5a antibody, survivin antibody, BIR1 antibody, Su2 antibody, XBIR1 antibody, XSurvivin1 antibody, Xsvv1 antibody, api4 antibody, bir1-A antibody, epr-1 antibody, svv1 antibody, xSurvivin antibody, xsurv antibody, Su1 antibody, birc5.2 antibody, svv2 antibody, xSurvivin2 antibody, bir5b antibody, SIX antibody, birc5.2-a antibody, birc5.2-b antibody, baculoviral IAP repeat containing 5 antibody, baculoviral IAP repeat-containing 5 antibody, baculoviral IAP repeat containing 5a antibody, baculoviral IAP repeat-containing 5, gene 1 L homeolog antibody, baculoviral IAP repeat containing 5 L homeolog antibody, baculoviral IAP repeat containing 5b antibody, baculoviral IAP repeat containing 5 S homeolog antibody, BIRC5 antibody, Birc5 antibody, birc5a antibody, birc5.1.L antibody, birc5.2.L antibody, birc5b antibody, birc5.2.S antibody
Background
This gene is a member of the inhibitor of apoptosis (IAP) gene family, which encode negative regulatory proteins that prevent apoptotic cell death. IAP family members usually contain multiple baculovirus IAP repeat (BIR) domains, but this gene encodes proteins with only a single BIR domain. The encoded proteins also lack a C-terminus RING finger domain. Gene expression is high during fetal development and in most tumors, yet low in adult tissues. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Gene ID
332
UniProt
O15392
Pathways
Apoptosis , Cell Division Cycle , Nuclear Hormone Receptor Binding
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