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FOXO3 antibody (Ser253)

This Rabbit Polyclonal antibody specifically detects FOXO3 in WB, ELISA, IF and IHC (p). It exhibits reactivity toward Human, Mouse and Rat.
Catalog No. ABIN5958398

Quick Overview for FOXO3 antibody (Ser253) (ABIN5958398)

Target

See all FOXO3 Antibodies
FOXO3 (Forkhead Box O3 (FOXO3))

Reactivity

  • 124
  • 80
  • 71
  • 9
  • 7
  • 6
  • 6
  • 5
  • 5
  • 4
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
Human, Mouse, Rat

Host

  • 125
  • 6
  • 1
  • 1
Rabbit

Clonality

  • 110
  • 23
Polyclonal

Conjugate

  • 79
  • 7
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This FOXO3 antibody is un-conjugated

Application

  • 97
  • 55
  • 51
  • 33
  • 22
  • 22
  • 20
  • 15
  • 15
  • 14
  • 4
  • 3
  • 2
  • 2
  • 1
  • 1
Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • Binding Specificity

    • 38
    • 9
    • 8
    • 8
    • 8
    • 7
    • 7
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Ser253

    Specificity

    AF6q21,AF6q21 protein,DKFZp781A0677,FKHR2,FKHRL 1,FKHRL1,FKHRL1P2,Forkhead (Drosophila) homolog (rhabdomyosarcoma) like 1,Forkhead box O3,Forkhead box O3A,Forkhead box protein O3,Forkhead box protein O3A,Forkhead Drosophila homolog of in rhabdomyosarcoma like 1,Forkhead homolog (rhabdomyosarcoma) like 1,Forkhead in rhabdomyosarcoma like 1,Forkhead in rhabdomyosarcoma-like 1,FOX O3A,FOXO2,foxo3,FOXO3,FOXO3A,MGC12739,MGC31925

    Purification

    Affinity purification

    Immunogen

    Synthesized peptide derived from human FoxO3A around the non-phosphorylation site of Ser253.

    Isotype

    IgG
  • Application Notes

    WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:20000

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1 mg/mL

    Buffer

    PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol, pH 7.4

    Preservative

    Sodium azide

    Precaution of Use

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Storage

    -20 °C

    Storage Comment

    Store at -20°C. Avoid freeze / thaw cycles.
  • Target

    FOXO3 (Forkhead Box O3 (FOXO3))

    Alternative Name

    FOXO3

    Background

    Transcriptional activator which triggers apoptosis in the absence of survival factors, including neuronal cell death upon oxidative stress. Recognizes and binds to the DNA sequence 5'-[AG]TAAA[TC]A-3'.

    Molecular Weight

    71kDa

    Gene ID

    2309

    UniProt

    O43524

    Pathways

    Cell Division Cycle, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Carbohydrate Homeostasis
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