FOXO3 antibody (Ser253)
Quick Overview for FOXO3 antibody (Ser253) (ABIN5958398)
Target
See all FOXO3 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- Ser253
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Specificity
- AF6q21,AF6q21 protein,DKFZp781A0677,FKHR2,FKHRL 1,FKHRL1,FKHRL1P2,Forkhead (Drosophila) homolog (rhabdomyosarcoma) like 1,Forkhead box O3,Forkhead box O3A,Forkhead box protein O3,Forkhead box protein O3A,Forkhead Drosophila homolog of in rhabdomyosarcoma like 1,Forkhead homolog (rhabdomyosarcoma) like 1,Forkhead in rhabdomyosarcoma like 1,Forkhead in rhabdomyosarcoma-like 1,FOX O3A,FOXO2,foxo3,FOXO3,FOXO3A,MGC12739,MGC31925
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Purification
- Affinity purification
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Immunogen
- Synthesized peptide derived from human FoxO3A around the non-phosphorylation site of Ser253.
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Isotype
- IgG
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Application Notes
- WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:20000
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol, pH 7.4
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- FOXO3 (Forkhead Box O3 (FOXO3))
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Alternative Name
- FOXO3
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Background
- Transcriptional activator which triggers apoptosis in the absence of survival factors, including neuronal cell death upon oxidative stress. Recognizes and binds to the DNA sequence 5'-[AG]TAAA[TC]A-3'.
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Molecular Weight
- 71kDa
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Gene ID
- 2309
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UniProt
- O43524
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Pathways
- Cell Division Cycle, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Carbohydrate Homeostasis
Target
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