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FAS antibody
FAS
Reactivity: Human, Mouse
WB, IHC
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-FAS Antibody
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Target
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FAS
(TNF Receptor Superfamily, Member 6 (FAS))
Reactivity
All reactivities for FAS antibodies
Human, Mouse
Host
All hosts for FAS antibodies
Rabbit
Clonality
All clonalities for FAS antibodies
Polyclonal
Conjugate
All conjugates for FAS antibodies
This FAS antibody is un-conjugated
Application
All applications for FAS antibodies
Western Blotting (WB), Immunohistochemistry (IHC)
Specificity
ALPS 1A,ALPS1A,APO 1,Apo 1 antigen,APO 1 cell surface antigen,Apo-1 antigen,APO1,Apo1 antigen,APO1 cell surface antigen,Apoptosis antigen 1,Apoptosis mediating surface antigen FAS,Apoptosis-mediating surface antigen FAS,APT 1,APT1,CD 95,CD 95 antigen,CD95,CD95 antigen,Delta Fas,Delta Fas/APO 1/CD95,Delta Fas/APO1/CD95,Fas (TNF receptor superfamily,member 6),FAS 1,FAS 827dupA,Fas AMA,Fas,FAS Antigen,Fas cell surface death receptor,FAS1,FASLG receptor,FASTM,sFAS,Surface antigen APO1,TNF receptor superfamily,member 6,TNFRSF 6,TNFRSF6,TNR6,Tumor necrosis factor receptor superfamily member 6
Purification
Affinity purification
Immunogen
Recombinant human Tumor necrosis factor receptor superfamily member 6 protein
Isotype
IgG
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Alternatives
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Application Details
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Application Notes
WB 1:500-1:1000, IHC 1:50-1:100
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
2 mg/mL
Buffer
PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Store at -20°C. Avoid freeze / thaw cycles.
Target Details for FAS
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Target
FAS
(TNF Receptor Superfamily, Member 6 (FAS))
Alternative Name
FAS (FAS Products )
Synonyms
ALPS1A antibody, APO-1 antibody, APT1 antibody, CD95 antibody, FAS1 antibody, FASTM antibody, TNFRSF6 antibody, AI196731 antibody, APO1 antibody, TNFR6 antibody, Tnfrsf6 antibody, lpr antibody, Fas cell surface death receptor antibody, Fas (TNF receptor superfamily member 6) antibody, FAS antibody, Fas antibody, fas antibody
Background
Fas (CD95/APO-1) is a transmembrane glycoprotein belonging to the tumor necrosis factor (TNF) receptor superfamily. It can mediates apoptosis by ligation with an agonistic anti-Fas antibody or Fas ligand. Stimulation of Fas results in the aggregation of its intracellular death domains, leading to the formation of the death-inducing signaling complex (DISC). FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells,or both. The molecular mass of native Fas is 38 kDa, the high molecular weight form (40-55 kDa) of Fas is due to glycosylation.
Molecular Weight
37kDa
Gene ID
355
UniProt
P25445
Pathways
p53 Signaling , Apoptosis , Production of Molecular Mediator of Immune Response , Positive Regulation of Endopeptidase Activity
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