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NRF2 antibody
NFE2L2
Reactivity: Human, Mouse, Rat
WB, ELISA, IF, IHC (p)
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-NRF2 Antibody
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Target
See all NRF2 (NFE2L2) Antibodies
NRF2 (NFE2L2)
(Nuclear Factor (erythroid-Derived 2)-Like 2 (NFE2L2))
Reactivity
All reactivities for NRF2 antibodies
Human, Mouse, Rat
Host
All hosts for NRF2 antibodies
Rabbit
Clonality
All clonalities for NRF2 antibodies
Polyclonal
Conjugate
All conjugates for NRF2 antibodies
This NRF2 antibody is un-conjugated
Application
All applications for NRF2 antibodies
Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Specificity
Erythroid derived 2,HEBP1,like 2,NF E2 related factor 2,NF-E2-related factor 2,NF2L2,NFE2 related factor 2,NFE2-related factor 2,Nfe2l2,Nrf 2,NRF2,Nuclear factor (erythroid derived 2) like 2,Nuclear factor,nuclear factor erythroid 2 like 2,Nuclear factor erythroid 2 related factor 2,Nuclear factor erythroid 2-related factor 2,Nuclear factor erythroid derived 2 like 2
Purification
Affinity purification
Immunogen
Synthesized peptide derived from the C-terminal region of human Nrf2
Isotype
IgG
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Alternatives
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Application Details
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Application Notes
WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:40000
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
1 mg/mL
Buffer
PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol, pH 7.4
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Store at -20°C. Avoid freeze / thaw cycles.
Target Details for NRF2
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Target
NRF2 (NFE2L2)
(Nuclear Factor (erythroid-Derived 2)-Like 2 (NFE2L2))
Alternative Name
Nrf2 (NFE2L2 Products )
Synonyms
Nrf2 antibody, nfe2l2 antibody, wu:fc15g09 antibody, wu:fj67e03 antibody, NF-E2R2 antibody, NRF2 antibody, AI194320 antibody, nuclear factor, erythroid 2-like 2a antibody, nuclear factor, erythroid 2 like 2 S homeolog antibody, nuclear factor, erythroid 2 like 2 antibody, nuclear factor, erythroid derived 2, like 2 antibody, nuclear factor, erythroid 2-like 2 antibody, nfe2l2a antibody, nfe2l2.S antibody, NFE2L2 antibody, Nfe2l2 antibody
Background
Transcription activator that binds to antioxidant response (ARE) elements in the promoter regions of target genes. Important for the coordinated up-regulation of genes in response to oxidative stress. May be involved in the transcriptional activation of genes of the beta-globin cluster by mediating enhancer activity of hypersensitive site 2 of the beta-globin locus control region.
Molecular Weight
75-100kDa
Gene ID
4780
UniProt
Q16236
Pathways
ER-Nucleus Signaling , Negative Regulation of intrinsic apoptotic Signaling
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