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PDGFRB antibody (Tyr751)
PDGFRB
Reactivity: Human, Mouse, Rat
WB, ELISA, IF, IHC (p)
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-PDGFRB Antibody
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Target
See all PDGFRB Antibodies
PDGFRB
(Platelet Derived Growth Factor Receptor beta (PDGFRB))
Binding Specificity
All epitopes for PDGFRB antibodies
Tyr751
Reactivity
All reactivities for PDGFRB antibodies
Human, Mouse, Rat
Host
All hosts for PDGFRB antibodies
Rabbit
Clonality
All clonalities for PDGFRB antibodies
Polyclonal
Conjugate
All conjugates for PDGFRB antibodies
This PDGFRB antibody is un-conjugated
Application
All applications for PDGFRB antibodies
Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Specificity
Beta platelet derived growth factor receptor,Beta-type platelet-derived growth factor receptor,CD 140B,CD140 antigen-like family member B,CD140b,CD140b antigen,IBGC4,IMF1,JTK12,OTTHUMP00000160528,PDGF R beta,PDGF-R-beta,PDGFR 1,PDGFR,PDGFR beta,PDGFR1,PDGFRB,PGFRB,Platelet derived growth factor receptor 1,Platelet derived growth factor receptor beta,Platelet derived growth factor receptor beta polypeptide
Purification
Affinity purification
Immunogen
Synthesized peptide derived from human PDGFR-beta around the non-phosphorylation site of Tyr751.
Isotype
IgG
Top Product
Discover our top product PDGFRB Primary Antibody
Alternatives
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Application Details
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Application Notes
WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:40000
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
1 mg/mL
Buffer
PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol, pH 7.4
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Store at -20°C. Avoid freeze / thaw cycles.
Target Details for PDGFRB
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Target
PDGFRB
(Platelet Derived Growth Factor Receptor beta (PDGFRB))
Alternative Name
PDGFRB (PDGFRB Products )
Synonyms
AI528809 antibody, CD140b antibody, PDGFR-1 antibody, Pdgfr antibody, CD140B antibody, IBGC4 antibody, JTK12 antibody, PDGFR antibody, PDGFR1 antibody, platelet derived growth factor receptor, beta polypeptide antibody, platelet derived growth factor receptor beta antibody, Pdgfrb antibody, PDGFRB antibody
Background
This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. This gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor, all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses this gene to that of the translocation, ETV6, leukemia gene, results in chronic myeloproliferative disorder with eosinophilia.
Molecular Weight
124kDa
Gene ID
5159
UniProt
P09619
Pathways
Fc-epsilon Receptor Signaling Pathway , EGFR Signaling Pathway , Neurotrophin Signaling Pathway , Inositol Metabolic Process , Glycosaminoglycan Metabolic Process , Smooth Muscle Cell Migration , Platelet-derived growth Factor Receptor Signaling
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