NR4A1 antibody (Ser351)

Catalog No. ABIN5961748

Product Details anti-NR4A1 Antibody

Target: NR4A1 (Nuclear Receptor Subfamily 4, Group A, Member 1 (NR4A1))

Binding Specificity: Ser351

Reactivity: Human, Mouse, Rat, Monkey

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NR4A1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificity: Early response protein NAK1,GFRP 1,GFRP,GFRP1,Growth factor inducible nuclear protein N10,Growth Factor Inducible Nuclear Protein NP10,Growth Factor Response Protein 1,Hbr1,HMR,Hormone Receptor,MGC9485,N10,N10 nuclear protein,NAK 1,NAK1,Nerve growth factor IB nuclear receptor variant 1,NGFIB,NP 10,NP10,NR4A1,NR4A1,Nuclear hormone receptor NUR/77,Nuclear Hormone Receptor TR3,Nuclear receptor subfamily 4 group A member 1,NUR77,NUR77,mouse,homolog of,Orphan nuclear receptor HMR,Orphan nuclear receptor NR4A1,Orphan nuclear receptor TR3,Orphan receptor tr3,Receptor NGFIB,ST 59,ST-59,ST59,Steroid receptor TR3,Testicular receptor 3,TR 3,TR3,TR3 orphan receptor

Purification: Affinity purification

Immunogen: Synthesized peptide derived from human Nur77 around the non-phosphorylation site of Ser351.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:10000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol,  pH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for NR4A1

Target: NR4A1 (Nuclear Receptor Subfamily 4, Group A, Member 1 (NR4A1))

Alternative Name: Nur77 (NR4A1 Products)

Synonyms: GFRP1 antibody, HMR antibody, N10 antibody, NAK-1 antibody, NGFIB antibody, NP10 antibody, NUR77 antibody, TR3 antibody, NGFI-B antibody, Gfrp antibody, Hbr-1 antibody, Hbr1 antibody, Hmr antibody, TIS1 antibody, nur77 antibody, Ngfi-b antibody, Nur77 antibody, nuclear receptor subfamily 4 group A member 1 antibody, nuclear receptor subfamily 4, group A, member 1 antibody, NR4A1 antibody, Nr4a1 antibody

Background: This gene encodes a member of the steroid-thyroid hormone-retinoid receptor superfamily. Expression is induced by phytohemagglutinin in human lymphocytes and by serum stimulation of arrested fibroblasts. The encoded protein acts as a nuclear transcription factor. Translocation of the protein from the nucleus to mitochondria induces apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene.

Molecular Weight: 64kDa

Gene ID: 3164

UniProt: P22736

Pathways: Fc-epsilon Receptor Signaling Pathway, Nuclear Receptor Transcription Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Steroid Hormone Mediated Signaling Pathway