ATP7B antibody
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- Target See all ATP7B Antibodies
- ATP7B (ATPase, Cu++ Transporting, beta Polypeptide (ATP7B))
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Reactivity
- Human, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This ATP7B antibody is un-conjugated
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Application
- Immunofluorescence (IF)
- Purification
- Affinity purification
- Immunogen
- Recombinant fusion protein of human ATP7B (NP_001230111.1).
- Isotype
- IgG
- Top Product
- Discover our top product ATP7B Primary Antibody
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- Application Notes
- IF 1:50-1:200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- ATP7B (ATPase, Cu++ Transporting, beta Polypeptide (ATP7B))
- Alternative Name
- ATP7B (ATP7B Products)
- Synonyms
- PWD antibody, WC1 antibody, WD antibody, WND antibody, Atp7a antibody, tx antibody, Hts antibody, PINA antibody, Wd antibody, ATP7B antibody, ATPase copper transporting beta antibody, ATPase, Cu++ transporting, beta polypeptide antibody, ATPase, Cu++ transporting, beta polypeptide (Wilson disease) antibody, copper-transporting ATPase 2 antibody, ATP7B antibody, Atp7b antibody, atp7b antibody, LOC592143 antibody
- Background
- This gene is a member of the P-type cation transport ATPase family and encodes a protein with several membrane-spanning domains, an ATPase consensus sequence, a hinge domain, a phosphorylation site, and at least 2 putative copper-binding sites. This protein functions as a monomer, exporting copper out of the cells, such as the efflux of hepatic copper into the bile. Alternate transcriptional splice variants, encoding different isoforms with distinct cellular localizations, have been characterized. Mutations in this gene have been associated with Wilson disease (WD).
- Molecular Weight
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Observed_MW: 150kDa
Calculated_MW: 133kDa/145kDa/155kDa/157kDa
- Gene ID
- 540
- UniProt
- P35670
- Pathways
- Transition Metal Ion Homeostasis, Ribonucleoside Biosynthetic Process
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