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ATP7B antibody

ATP7B Reactivity: Human, Mouse IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN5962914
  • Target See all ATP7B Antibodies
    ATP7B (ATPase, Cu++ Transporting, beta Polypeptide (ATP7B))
    Reactivity
    • 37
    • 26
    • 21
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Mouse
    Host
    • 39
    • 21
    Rabbit
    Clonality
    • 39
    • 21
    Polyclonal
    Conjugate
    • 23
    • 8
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ATP7B antibody is un-conjugated
    Application
    • 41
    • 22
    • 18
    • 16
    • 13
    • 13
    • 13
    • 9
    • 9
    • 6
    • 4
    • 2
    • 2
    • 1
    Immunofluorescence (IF)
    Purification
    Affinity purification
    Immunogen
    Recombinant fusion protein of human ATP7B (NP_001230111.1).
    Isotype
    IgG
    Top Product
    Discover our top product ATP7B Primary Antibody
  • Application Notes
    IF 1:50-1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    ATP7B (ATPase, Cu++ Transporting, beta Polypeptide (ATP7B))
    Alternative Name
    ATP7B (ATP7B Products)
    Synonyms
    PWD antibody, WC1 antibody, WD antibody, WND antibody, Atp7a antibody, tx antibody, Hts antibody, PINA antibody, Wd antibody, ATP7B antibody, ATPase copper transporting beta antibody, ATPase, Cu++ transporting, beta polypeptide antibody, ATPase, Cu++ transporting, beta polypeptide (Wilson disease) antibody, copper-transporting ATPase 2 antibody, ATP7B antibody, Atp7b antibody, atp7b antibody, LOC592143 antibody
    Background
    This gene is a member of the P-type cation transport ATPase family and encodes a protein with several membrane-spanning domains, an ATPase consensus sequence, a hinge domain, a phosphorylation site, and at least 2 putative copper-binding sites. This protein functions as a monomer, exporting copper out of the cells, such as the efflux of hepatic copper into the bile. Alternate transcriptional splice variants, encoding different isoforms with distinct cellular localizations, have been characterized. Mutations in this gene have been associated with Wilson disease (WD).
    Molecular Weight

    Observed_MW: 150kDa

    Calculated_MW: 133kDa/145kDa/155kDa/157kDa

    Gene ID
    540
    UniProt
    P35670
    Pathways
    Transition Metal Ion Homeostasis, Ribonucleoside Biosynthetic Process
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