BMPR1A antibody

Catalog No. ABIN5963019

Product Details anti-BMPR1A Antibody

Target: BMPR1A (Bone Morphogenetic Protein Receptor 1A (BMPR1A))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BMPR1A antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Affinity purification

Immunogen: Recombinant protein of human BMPR1A

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for BMPR1A

Target: BMPR1A (Bone Morphogenetic Protein Receptor 1A (BMPR1A))

Alternative Name: CD292 (BMPR1A Products)

Synonyms: 10q23del antibody, ACVRLK3 antibody, ALK3 antibody, CD292 antibody, SKR5 antibody, 1110037I22Rik antibody, AU045487 antibody, BMPR-IA antibody, Bmpr antibody, BMPR-1 antibody, BRK-1 antibody, BMPR1A antibody, acvrlk3 antibody, alk-3 antibody, alk3 antibody, cd292 antibody, skr5 antibody, BR1a antibody, alk3tr antibody, bmpr1a antibody, zgc:136731 antibody, wu:fe05b06 antibody, wu:fe06e10 antibody, zgc:92227 antibody, bone morphogenetic protein receptor type 1A antibody, bone morphogenetic protein receptor, type 1A antibody, bone morphogenetic protein receptor type 1A S homeolog antibody, bone morphogenetic protein receptor, type IAa antibody, bone morphogenetic protein receptor, type IAb antibody, BMPR1A antibody, Bmpr1a antibody, bmpr1a antibody, bmpr1a.S antibody, bmpr1aa antibody, bmpr1ab antibody

Background:

Synonyms: 10q23del,Activin A receptor type II like kinase 3,Activin receptor like kinase 3,Activin receptor-like kinase 3,ACVRLK 3,ACVRLK3,ALK 3,ALK-3,ALK3,BMP type-1A receptor,BMPR 1A,Bmpr,BMPR-1A,Bmpr1a,BMR1A,Bone morphogenetic protein receptor type IA,Bone morphogenetic protein receptor type IA precursor,Bone morphogenetic protein receptor type-1A,BR 1a,BR1a,CD 292,CD292,CD292 antigen,EC 2.7.11.30,Serine threonine protein kinase receptor R5,Serine threonine protein kinase receptor R5 precursor,Serine/threonine-protein kinase receptor R5,SKR 5,SKR5,zBMPR IA,zBMPRIA

Background: The bone morphogenetic protein (BMP) receptors are a family of transmembrane serine/threonine kinases that include the type I receptors BMPR1A and BMPR1B and the type II receptor BMPR2. These receptors are also closely related to the activin receptors, ACVR1 and ACVR2. The ligands of these receptors are members of the TGF-beta superfamily. TGF-betas and activins transduce their signals through the formation of heteromeric complexes with 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding.

Molecular Weight:

Observed_MW: 69kDa

Calculated_MW: 60kDa

Gene ID: 657

UniProt: P36894

Pathways: Stem Cell Maintenance