FGF23 antibody

Catalog No. ABIN5963411

Product Details anti-FGF23 Antibody

Target: FGF23 (Fibroblast Growth Factor 23 (FGF23))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FGF23 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Affinity purification

Immunogen: Recombinant protein of human FGF23

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for FGF23

Target: FGF23 (Fibroblast Growth Factor 23 (FGF23))

Alternative Name: FGF23 (FGF23 Products)

Synonyms: FGF23 antibody, ADHR antibody, FGFN antibody, HPDR2 antibody, HYPF antibody, PHPTC antibody, fibroblast growth factor 23 antibody, fgf23 antibody, FGF23 antibody, Fgf23 antibody

Background:

Synonyms: ADHR,FGF-23,Fgf23,FGF23,FGFN,Fibroblast growth factor 23,Fibroblast growth factor 23 C-terminal peptide,Fibroblast growth factor 23 precursor,HPDR2,HYPF,Phosphatonin,PHPTC,Tumor derived hypophosphatemia inducing factor,Tumor-derived hypophosphatemia-inducing factor

Background: This gene encodes a member of the fibroblast growth factor family of proteins, which possess broad mitogenic and cell survival activities and are involved in a variety of biological processes. The product of this gene regulates phosphate homeostasis and transport in the kidney. The full-length, functional protein may be deactivated via cleavage into N-terminal and C-terminal chains. Mutation of this cleavage site causes autosomal dominant hypophosphatemic rickets (ADHR). Mutations in this gene are also associated with hyperphosphatemic familial tumoral calcinosis (HFTC).

Molecular Weight:

Observed_MW: 28kDa

Calculated_MW: 27kDa

Gene ID: 8074

UniProt: Q9GZV9

Pathways: RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Negative Regulation of Hormone Secretion