FUS antibody

Catalog No. ABIN5963452

Product Details anti-FUS Antibody

Target: FUS (Fused in Sarcoma (FUS))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FUS antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Affinity purification

Immunogen: Recombinant protein of human FUS

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for FUS

Target: FUS (Fused in Sarcoma (FUS))

Alternative Name: FUS (FUS Products)

Synonyms: ALS6 antibody, ETM4 antibody, FUS1 antibody, HNRNPP2 antibody, POMP75 antibody, TLS antibody, D430004D17Rik antibody, D930039C12Rik antibody, Fus1 antibody, Tls antibody, FUS/TLS antibody, FUS RNA binding protein antibody, fused in sarcoma antibody, FUS antibody, Fus antibody

Target Type: Viral Protein

Background:

Synonyms: 75 kDa DNA pairing protein,75 kDa DNA-pairing protein,ALS6,Amyotrophic lateral sclerosis 6,fus,FUS CHOP,Fus like protein,FUS,FUS1,Fused in sarcoma,Fusion (involved in t(12,16) in malignant liposarcoma),Fusion derived from t(12,16) malignant liposarcoma,Fusion gene in myxoid liposarcoma,Heterogeneous nuclear ribonucleoprotein P2,hnRNP P2,hnRNPP2,Oncogene FUS,Oncogene TLS,POMp75,RNA binding protein FUS,RNA-binding protein FUS,TLS,TLS CHOP,Translocated in liposarcoma,Translocated in liposarcoma protein

Background: This gene encodes a multifunctional protein component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complex. The hnRNP complex is involved in pre-mRNA splicing and the export of fully processed mRNA to the cytoplasm. This protein belongs to the FET family of RNA-binding proteins which have been implicated in cellular processes that include regulation of gene expression, maintenance of genomic integrity and mRNA/microRNA processing. Alternative splicing results in multiple transcript variants. Defects in this gene result in amyotrophic lateral sclerosis type 6.

Molecular Weight:

Observed_MW: 70kDa

Calculated_MW: 53kDa

Gene ID: 2521

UniProt: P35637