Oncostatin M antibody
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- Target See all Oncostatin M (OSM) Antibodies
- Oncostatin M (OSM)
- Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This Oncostatin M antibody is un-conjugated
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Application
- Immunohistochemistry (IHC), Immunofluorescence (IF)
- Purification
- Affinity purification
- Immunogen
- Recombinant fusion protein of human OSM (NP_065391.1).
- Isotype
- IgG
- Top Product
- Discover our top product OSM Primary Antibody
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- Application Notes
- IHC 1:50-1:100 IF 1:50-1:200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- Oncostatin M (OSM)
- Alternative Name
- OSM (OSM Products)
- Synonyms
- OSM antibody, OncoM antibody, oncostatin M antibody, OSM antibody, Osm antibody
- Background
- This gene encodes a member of the leukemia inhibitory factor/oncostatin-M (LIF/OSM) family of proteins. The encoded preproprotein is proteolytically processed to generate the mature protein. This protein is a secreted cytokine and growth regulator that inhibits the proliferation of a number of tumor cell lines. This protein also regulates the production of other cytokines, including interleukin 6, granulocyte-colony stimulating factor and granulocyte-macrophage colony stimulating factor in endothelial cells. This gene and the related gene, leukemia inhibitory factor, also present on chromosome 22, may have resulted from the duplication of a common ancestral gene. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.
- Molecular Weight
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Observed_MW: 28kDa
Calculated_MW: 28kDa
- Gene ID
- 5008
- UniProt
- P13725
- Pathways
- JAK-STAT Signaling, Negative Regulation of Hormone Secretion
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