Cadherin 5 antibody

Catalog No. ABIN5964584

Product Details anti-Cadherin 5 Antibody

Target: Cadherin 5 (CDH5)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Cadherin 5 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Affinity purification

Immunogen: Recombinant protein of human CDH5

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:1000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Cadherin 5

Target: Cadherin 5 (CDH5)

Alternative Name: VE-Cadherin (CDH5 Products)

Synonyms: 7B4 antibody, AA408225 antibody, Cd144 antibody, VE-Cad antibody, VECD antibody, VEcad antibody, Vec antibody, wu:fc88a07 antibody, CD144 antibody, cadherin-5 antibody, cadherin 5 antibody, CDH5 antibody, Cdh5 antibody, cdh5 antibody

Background:

Synonyms: 7B 4,7B4,7B4 antigen,CADH5,Cadherin 5,Cadherin 5 type 2,Cadherin 5,type 2 (vascular endothelium),Cadherin 5,type 2,VE cadherin (vascular epithelium),cadherin,vascular endothelial,cadherin,vascular endothelial,1,Cadherin-5,Cadherin5,CD 144,CD144,CD144 antigen,CDH 5,CDH5,CDH5 protein,Endothelial specific cadherin,FLJ17376,OTTHUMP00000174777,Vascular endothelial cadherin,Vascular epithelium cadherin,VE Cad,VE-cadherin,VEC

Background: This gene encodes a classical cadherin of the cadherin superfamily. The encoded preproprotein is proteolytically processed to generate the mature glycoprotein. This calcium-dependent cell-cell adhesion molecule is comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Functioning as a classical cadherin by imparting to cells the ability to adhere in a homophilic manner, this protein plays a role in endothelial adherens junction assembly and maintenance. This gene is located in a gene cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer.

Molecular Weight:

Observed_MW: 120kDa

Calculated_MW: 74kDa/87kDa

Gene ID: 1003

UniProt: P33151

Pathways: Cell-Cell Junction Organization, Signaling Events mediated by VEGFR1 and VEGFR2