BAK1 antibody
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- Target See all BAK1 Antibodies
- BAK1 (BCL2-Antagonist/killer 1 (BAK1))
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This BAK1 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunofluorescence (IF)
- Purification
- Affinity purification
- Immunogen
- A synthetic peptide of human BAK1 (NP_001179.1).
- Isotype
- IgG
- Top Product
- Discover our top product BAK1 Primary Antibody
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- Application Notes
- WB 1:500-1:2000 IF 1:50-1:200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- Preservative
- Sodium azide
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- BAK1 (BCL2-Antagonist/killer 1 (BAK1))
- Alternative Name
- BAK1 (BAK1 Products)
- Synonyms
- BAK antibody, BAK-LIKE antibody, BCL2L7 antibody, CDN1 antibody, Bak antibody, N-BAK1 antibody, N-Bak antibody, Bak1 antibody, bak antibody, bak1 antibody, BCL2 antagonist/killer 1 antibody, BCL2-antagonist/killer 1 antibody, BCL2 antagonist/killer 1 L homeolog antibody, BAK1 antibody, Bak1 antibody, bak1.L antibody
- Background
- The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress.
- Molecular Weight
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Observed_MW: 26kDa
Calculated_MW: 16kDa/23kDa
- Gene ID
- 578
- UniProt
- Q16611
- Pathways
- Apoptosis, Steroid Hormone Mediated Signaling Pathway, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Unfolded Protein Response
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