CrkL antibody
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- Target See all CrkL (CRKL) Antibodies
- CrkL (CRKL) (V-Crk Sarcoma Virus CT10 Oncogene Homolog (Avian)-Like (CRKL))
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Reactivity
- Human, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This CrkL antibody is un-conjugated
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Application
- Western Blotting (WB)
- Purification
- Affinity purification
- Immunogen
- A synthetic peptide of human CRKL
- Isotype
- IgG
- Top Product
- Discover our top product CRKL Primary Antibody
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- Application Notes
- WB 1:500 - 1:2000
- Restrictions
- For Research Use only
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- Concentration
- 1 mg/mL
- Buffer
- Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- CrkL (CRKL) (V-Crk Sarcoma Virus CT10 Oncogene Homolog (Avian)-Like (CRKL))
- Alternative Name
- CRKL (CRKL Products)
- Synonyms
- CRKL antibody, wu:fa55g05 antibody, wu:fj60e01 antibody, zgc:63469 antibody, 1110025F07Rik antibody, AA589403 antibody, AI325100 antibody, Crkol antibody, CRK like proto-oncogene, adaptor protein antibody, v-crk avian sarcoma virus CT10 oncogene homolog-like antibody, CRKL antibody, crkl antibody, Crkl antibody
- Background
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Synonyms: Crk L,Crk like protein,Crk-like protein,Crkl,CRKL,Crkol,HGNC:2363 ,Oncogene CrkL,V crk avian sarcoma virus CT10 oncogene homolog like,v crk sarcoma virus CT10 oncogene homolog (avian) like,V crk sarcoma virus CT10 oncogene homolog avian like
Background: This gene encodes a protein kinase containing SH2 and SH3 (src homology) domains which has been shown to activate the RAS and JUN kinase signaling pathways and transform fibroblasts in a RAS-dependent fashion. It is a substrate of the BCR-ABL tyrosine kinase, plays a role in fibroblast transformation by BCR-ABL, and may be oncogenic.
- Molecular Weight
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Observed_MW: 34kDa
Calculated_MW: 33kDa
- Gene ID
- 1399
- UniProt
- P46109
- Pathways
- Interferon-gamma Pathway, Neurotrophin Signaling Pathway, Signaling of Hepatocyte Growth Factor Receptor
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