DYRK1A antibody
-
- Target See all DYRK1A Antibodies
- DYRK1A (Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 1A (DYRK1A))
-
Reactivity
- Human, Mouse, Rat
-
Host
- Rabbit
-
Clonality
- Polyclonal
-
Conjugate
- This DYRK1A antibody is un-conjugated
-
Application
- Western Blotting (WB)
- Purification
- Affinity purification
- Immunogen
- Recombinant protein of human DYRK1A
- Isotype
- IgG
- Top Product
- Discover our top product DYRK1A Primary Antibody
-
-
- Application Notes
- WB 1:500 - 1:1000
- Restrictions
- For Research Use only
-
- Concentration
- 1 mg/mL
- Buffer
- Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
-
- Target
- DYRK1A (Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 1A (DYRK1A))
- Alternative Name
- DYRK1A (DYRK1A Products)
- Synonyms
- DYRK1A antibody, dyrk antibody, dyrk1 antibody, hp86 antibody, mnb antibody, mnbh antibody, DYRK antibody, DYRK1 antibody, HP86 antibody, MNB antibody, MNBH antibody, MRD7 antibody, 2310043O08Rik antibody, D16Ertd272e antibody, D16Ertd493e antibody, Dyrk antibody, ENSMUSG00000074897 antibody, Gm10783 antibody, Mnbh antibody, Mp86 antibody, mmb antibody, PSK47 antibody, dual specificity tyrosine phosphorylation regulated kinase 1A antibody, dual specificity tyrosine-(Y)-phosphorylation regulated kinase 1A antibody, dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1a antibody, dual specificity tyrosine-(Y)-phosphorylation regulated kinase 1A S homeolog antibody, DYRK1A antibody, dyrk1a antibody, Dyrk1a antibody, dyrk1a.S antibody
- Background
-
Synonyms: Dual specificity tyrosine phosphorylation regulated kinase,Dual specificity tyrosine (Y) phosphorylation regulated kinase 1A,Dual specificity tyrosine phosphorylation regulated kinase 1,Dual specificity tyrosine phosphorylation regulated kinase 1A,Dual specificity tyrosine-phosphorylation-regulated kinase 1A,Dual specificity YAK 1 related kinase,Dual specificity YAK1 related kinase,Dual specificity YAK1-related kinase,DYR1A,DYRK 1,DYRK 1A,DYRK,DYRK1,Dyrk1a,DYRKA,hMNB,HP 86,HP86,Minibrain (Drosophila) homolog,Minibrain homolog,Minibrain,Drosophila,homolog of,MNB,MNB protein kinase,Mnb protein kinase homolog hp86,MNB protein kinase,Serine/threonine-specific,MNB/DYRK protein kinase,MNBH,MRD7,OTTHUMP00000109090,OTTHUMP00000109091,OTTHUMP00000109094,OTTHUMP00000174799,Protein kinase minibrain homolog,Serine/threonine kinase MNB
Background: This gene encodes a member of the Dual-specificity tyrosine phosphorylation-regulated kinase (DYRK) family. This member contains a nuclear targeting signal sequence, a protein kinase domain, a leucine zipper motif, and a highly conservative 13-consecutive-histidine repeat. It catalyzes its autophosphorylation on serine/threonine and tyrosine residues. It may play a significant role in a signaling pathway regulating cell proliferation and may be involved in brain development. This gene is a homolog of Drosophila mnb (minibrain) gene and rat Dyrk gene. It is localized in the Down syndrome critical region of chromosome 21, and is considered to be a strong candidate gene for learning defects associated with Down syndrome. Alternative splicing of this gene generates several transcript variants differing from each other either in the 5' UTR or in the 3' coding region. These variants encode at least five different isoforms.
- Molecular Weight
-
Observed_MW: 72kDa
Calculated_MW: 60kDa/61kDa/66kDa/84kDa/85kDa
- Gene ID
- 1859
- UniProt
- Q13627
- Pathways
- Mitotic G1-G1/S Phases
-