NONO antibody

Catalog No. ABIN5967294

Product Details anti-NONO Antibody

Target: NONO (Non-POU Domain Containing, Octamer-Binding (NONO))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NONO antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Purification: Affinity purification

Immunogen: Recombinant protein of human Nono

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for NONO

Target: NONO (Non-POU Domain Containing, Octamer-Binding (NONO))

Alternative Name: NONO (NONO Products)

Synonyms: NMT55 antibody, NRB54 antibody, P54 antibody, P54NRB antibody, nmt55 antibody, nrb54 antibody, p54nrb antibody, xp54nrb antibody, AA407051 antibody, AV149256 antibody, nonA antibody, non-POU domain containing octamer binding antibody, non-POU domain containing, octamer-binding antibody, non-POU domain containing, octamer binding L homeolog antibody, non-POU-domain-containing, octamer binding protein antibody, NONO antibody, Nono antibody, nono.L antibody

Background:

Synonyms: 52 kDa subunit,54 kDa nuclear RNA and DNA binding protein,54 kDa nuclear RNA- and DNA-binding protein,55 kDa nuclear protein,DNA binding p52/p100 complex 52 kDa subunit,DNA-binding p52/p100 complex,NMT 55,NMT55,Non Pou domain containing octamer (ATGCAAAT) binding protein,Non POU domain containing octamer binding,Non POU domain containing octamer binding protein,Non-POU domain-containing octamer-binding protein,Nono,NonO protein,NONO,NRB 54,NRB,NRB54,Nuclear RNA binding protein 54kD,P54,p54(nrb),p54nrb,PPP1R114,Protein phosphatase 1 regulatory subunit 114

Background: This gene encodes an RNA-binding protein which plays various roles in the nucleus, including transcriptional regulation and RNA splicing. A rearrangement between this gene and the transcription factor E3 gene has been observed in papillary renal cell carcinoma. Alternatively spliced transcript variants have been described. Pseudogenes exist on Chromosomes 2 and 16.

Molecular Weight:

Observed_MW: 58kDa

Calculated_MW: 43kDa/54kDa

Gene ID: 4841

UniProt: Q15233