PARL antibody
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- Target See all PARL Antibodies
- PARL (Presenilin Associated, Rhomboid-Like (PARL))
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This PARL antibody is un-conjugated
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Application
- Western Blotting (WB), Immunofluorescence (IF)
- Purification
- Affinity purification
- Immunogen
- Recombinant fusion protein of human PARL (NP_001032728.1).
- Isotype
- IgG
- Top Product
- Discover our top product PARL Primary Antibody
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- Application Notes
- WB 1:500-1:2000 IF 1:50-1:200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- PARL (Presenilin Associated, Rhomboid-Like (PARL))
- Alternative Name
- PARL (PARL Products)
- Synonyms
- PSARL antibody, PSARL1 antibody, PSENIP2 antibody, RHBDS1 antibody, D16Ertd607e antibody, PRO2207 antibody, Psarl antibody, parl antibody, zgc:112986 antibody, presenilin associated rhomboid like antibody, presenilin associated, rhomboid-like antibody, presenilin associated, rhomboid-like a antibody, PARL antibody, Parl antibody, parla antibody
- Background
- This gene encodes a member of the rhomboid family of intramembrane serine proteases that is localized to the inner mitochondrial membrane. The encoded protein regulates mitochondrial remodeling and apoptosis through regulated substrate proteolysis. Proteolytic processing of the encoded protein results in the release of a small peptide, P-beta, which may transit to the nucleus. Mutations in this gene may be associated with Parkinson's disease.
- Molecular Weight
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Observed_MW: 42kDa
Calculated_MW: 36kDa/42kDa
- Gene ID
- 55486
- UniProt
- Q9H300
- Pathways
- Autophagy
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