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CHEK2 antibody (pThr383)

Name: CHEK2 antibody (pThr383)
SKU: ABIN1844022
Price: 533.08 USD
Availability: InStock

CHEK2 Reactivity: Human, Mouse, Rat WB, IF/ICC Host: Rabbit Polyclonal unconjugated

Western Blotting (WB) image for anti-Checkpoint Kinase 2 (CHEK2) (pThr383) antibody (ABIN1844022)

1 image

Catalog No. ABIN1844022

Datasheet as PDF

Target See all CHEK2 Antibodies

CHEK2 (Checkpoint Kinase 2 (CHEK2))
Binding Specificity
30

28

21

17

16

15

15

15

9

8

8

8

8

7

7

6

4

3

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
pThr383
Reactivity
261

96

82

16

14

7

6

5

2

2

2

1

1
Human, Mouse, Rat
Host
242

20

1

1
Rabbit
Compatible Secondaries
Clonality
228

36
Polyclonal
Conjugate
116

14

12

12

12

12

12

12

10

9

7

7

7

7

7

2

2

2

1

1
This CHEK2 antibody is un-conjugated
Application
206

80

79

72

37

36

33

28

28

19

18

5

1

1

1

1

1
Western Blotting (WB), Immunofluorescence (fixed cells) (IF/ICC)

Specificity

Phospho-Chk2 (Thr383) Antibody detects endogenous levels of Chk2 only when phosphorylated at Threonine 383.

Purification

Immunogen affinity purified

Immunogen

A synthesized peptide derived from human Chk2 around the phosphorylation site of Threonine 383.

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anti-Checkpoint Kinase 2 (CHEK2) (pThr383) antibody
CHEK2 Reactivity: Human, Mouse, Rat WB, ELISA, IHC, IF, ICC Host: Rabbit Polyclonal unconjugated

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CHEK2 Reactivity: Human WB, IP Host: Rabbit Polyclonal unconjugated

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CHEK2 Reactivity: Human WB, ELISA, IF, IHC (p) Host: Mouse Monoclonal 4B7 unconjugated

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CHEK2 Reactivity: Human, Monkey, Dog WB, IHC, IF, IHC (p), FACS Host: Mouse Monoclonal 10G7 unconjugated

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CHEK2 Reactivity: Human, Dog WB, IHC, IF, IHC (p), IP, FACS Host: Mouse Monoclonal 5C4 unconjugated

anti-Checkpoint Kinase 2 (CHEK2) antibody
CHEK2 Reactivity: Human, Dog WB, IHC, IHC (p), IP, FACS Host: Mouse Monoclonal 2H5 unconjugated

Restrictions

For Research Use only
Format

Liquid

Buffer

Rabbit IgG in PBS,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative

Sodium azide

Precaution of Use

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage

-20 °C

Storage Comment

Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles.
Target

CHEK2 (Checkpoint Kinase 2 (CHEK2))

Alternative Name

Chk2 (CHEK2 Products)

Synonyms

CDS1 antibody, CHK2 antibody, HuCds1 antibody, LFS2 antibody, PP1425 antibody, RAD53 antibody, hCds1 antibody, fa66f08 antibody, wu:fa66f08 antibody, zgc:55865 antibody, Cds1 antibody, HUCDS1 antibody, Rad53 antibody, Chk2 antibody, cds1 antibody, chek2 antibody, chk2 antibody, hucds1 antibody, lfs2 antibody, pp1425 antibody, rad53 antibody, checkpoint kinase 2 antibody, serine/threonine-protein kinase chk2 antibody, checkpoint kinase 2 L homeolog antibody, CHEK2 antibody, chek2 antibody, Chek2 antibody, MCYG_07308 antibody, chek2.L antibody

Background

In response to DNA damage and replication blocks, cell cycle progression is halted through the control of critical cell cycle regulators. The protein encoded by this gene is a cell cycle checkpoint regulator and putative tumor suppressor.

Molecular Weight

60 kDa

Gene ID

11200

UniProt

O96017

Pathways

p53 Signaling, Apoptosis, Cell Division Cycle