c-MYC antibody (AA 423-435)

Catalog No. ABIN609226

This Mouse Monoclonal antibody specifically detects c-MYC in IHC, ELISA, FACS, IHC (p) and IHC (fro). It exhibits reactivity toward Human.

Quick Overview for c-MYC antibody (AA 423-435) (ABIN609226)

Target: c-MYC (MYC) (Myc Proto-Oncogene protein (MYC))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This c-MYC antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-c-MYC Antibody

Binding Specificity: AA 423-435

Specificity: Recognizes the 62kD human c-myc gene product, which is involved in the regulation of the cell cycle and cell growth.

Predicted Reactivity: Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla (100%) Orangutan, Monkey, Marmoset, Tamarin (92%) Rat, Sheep, Hamster, Panda, Dog, Horse (85%).

Purification: Protein G purified

Immunogen: Synthetic peptide corresponding to the C-terminal region of human c-myc (AEEQKLISEEDLL). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla (100%), Orangutan, Monkey, Marmoset, Tamarin (92%), Rat, Sheep, Hamster, Panda, Dog, Horse (85%).

Type of Immunogen: Synthetic peptide

Isotype: IgG1

Application Details

Application Notes: Approved: ELISA (1:100 - 1:500), Flo, IHC, IHC-Fr, IHC-P

Usage: Suitable for use in ELISA, Flow Cytometry, and Immunohistochemistry (frozen and paraffin). ELISA: 1:100-1:500. Flow Cytometry: Neat-1:10, 10 μL labels 10^6 cells in 100 μL.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS,  pH 7.4, 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing

Storage: 4 °C,-20 °C

Storage Comment: May be stored at 4°C for short-term only. For long-term storage and to avoid freeze-thaw cycles, aliquot and store at -20°C. Aliquots are stable for at least 1 year at -20°C.

Target Details for c-MYC

Target: c-MYC (MYC) (Myc Proto-Oncogene protein (MYC))

Alternative Name: MYC / c-Myc

Background: Name/Gene ID: MYC

Synonyms: MYC, BHLHe39, C-Myc, MRTL, Myc proto-oncogene protein, Proto-oncogene c-Myc, Rats1, Transcription factor p64, v-myc

Gene ID: 4609

UniProt: P01106

Pathways: p53 Signaling, Cell Division Cycle, Sensory Perception of Sound, Transition Metal Ion Homeostasis, Mitotic G1-G1/S Phases, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Positive Regulation of Response to DNA Damage Stimulus, Warburg Effect