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MANF antibody (AA 25-182)
MANF
Reactivity: Human
WB, IHC
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-MANF Antibody
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Target
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MANF
(Mesencephalic Astrocyte-Derived Neurotrophic Factor (MANF))
Binding Specificity
All epitopes for MANF antibodies
AA 25-182
Reactivity
All reactivities for MANF antibodies
Human
Host
All hosts for MANF antibodies
Rabbit
Clonality
All clonalities for MANF antibodies
Polyclonal
Conjugate
All conjugates for MANF antibodies
This MANF antibody is un-conjugated
Application
All applications for MANF antibodies
Western Blotting (WB), Immunohistochemistry (IHC)
Sequence
SRALRPGDCE VCISYLGRFY QDLKDRDVTF SPATIENELI KFCREARGKE NRLCYYIGAT DDAATKIINE VSKPLAHHIP VEKICEKLKK KDSQICELKY DKQIDLSTVD LKKLRVKELK KILDDWGETC KGCAEKSDYI RKINELMPKY APKAASAR
Cross-Reactivity
Human, Mouse, Rat
Characteristics
Polyclonal Antibodies
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 25-182 of human ARMET/ARP/MANF (NP_006001.4).
Isotype
IgG
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Discover our top product MANF Primary Antibody
Alternatives
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Application Details
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Application Notes
WB,1:500 - 1:2000,IHC,1:50 - 1:200
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Store at -20°C. Avoid freeze / thaw cycles.
Target Details for MANF
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Target
MANF
(Mesencephalic Astrocyte-Derived Neurotrophic Factor (MANF))
Alternative Name
MANF (MANF Products )
Synonyms
ARMET antibody, ARP antibody, 3230402M22Rik antibody, AA407711 antibody, AA408789 antibody, AA673178 antibody, Armet antibody, D17914 antibody, D18Mgi17 antibody, MANF antibody, RBM15B antibody, ARP-like antibody, CG7013 antibody, DmMANF antibody, Dmel\\CG7013 antibody, anon-EST:ParkEST188 antibody, arp antibody, armet antibody, im:6909481 antibody, zgc:153327 antibody, manf antibody, mesencephalic astrocyte derived neurotrophic factor antibody, mesencephalic astrocyte-derived neurotrophic factor antibody, RNA binding motif protein 15B antibody, Mesencephalic astrocyte-derived neurotrophic factor antibody, mesencephalic astrocyte-derived neurotrophic factor S homeolog antibody, MANF antibody, Manf antibody, RBM15B antibody, manf antibody, manf.S antibody
Background
The protein encoded by this gene is localized in the endoplasmic reticulum (ER) and golgi, and is also secreted. Reducing expression of this gene increases susceptibility to ER stress-induced death and results in cell proliferation. Activity of this protein is important in promoting the survival of dopaminergic neurons. The presence of polymorphisms in the N-terminal arginine-rich region, including a specific mutation that changes an ATG start codon to AGG, have been reported in a variety of solid tumors, however, these polymorphisms were later shown to exist in normal tissues and are thus no longer thought to be tumor-related.,MANF,ARMET,ARP,Cancer,Cell Biology & Developmental Biology,Cell Cycle,Growth factor,Neuroscience,MANF
Molecular Weight
20 kDa
Gene ID
7873
UniProt
P55145
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