ASIC3 antibody (AA 62-320)

Catalog No. ABIN6137191

Product Details anti-ASIC3 Antibody

Target: ASIC3 (ACCN3) (Amiloride-Sensitive Cation Channel 3 (ACCN3))

Binding Specificity: AA 62-320

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ASIC3 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: ERVRYYREFH HQTALDERES HRLIFPAVTL CNINPLRRSR LTPNDLHWAG SALLGLDPAE HAAFLRALGR PPAPPGFMPS PTFDMAQLYA RAGHSLDDML LDCRFRGQPC GPENFTTIFT RMGKCYTFNS GADGAELLTT TRGGMGNGLD IMLDVQQEEY LPVWRDNEET PFEVGIRVQI HSQEEPPIID QLGLGVSPGY QTFVSCQQQQ LSFLPPPWGD CSSASLNPNY EPEPSDPLGS PSPSPSPPYT LMGCRLACE

Cross-Reactivity: Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 62-320 of human ASIC3 (NP_064717.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for ASIC3

Target: ASIC3 (ACCN3) (Amiloride-Sensitive Cation Channel 3 (ACCN3))

Alternative Name: ASIC3 (ACCN3 Products)

Synonyms: ACCN3 antibody, Accn3 antibody, DRASIC antibody, SLNAC1 antibody, TNaC1 antibody, AW742291 antibody, TNAC1 antibody, amiloride-sensitive cation channel 3 antibody, acid sensing ion channel subunit 3 antibody, acid-sensing (proton-gated) ion channel 3 antibody, ACCN3 antibody, ASIC3 antibody, Asic3 antibody

Background: This gene encodes a member of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. The members of this family are amiloride-sensitive sodium channels that contain intracellular N and C termini, two hydrophobic transmembrane regions, and a large extracellular loop, which has many cysteine residues with conserved spacing. The member encoded by this gene is an acid sensor and may play an important role in the detection of lasting pH changes. In addition, a heteromeric association between this member and acid-sensing (proton-gated) ion channel 2 has been observed as proton-gated channels sensitive to gadolinium. Alternatively spliced transcript variants have been described.,ASIC3,ACCN3,DRASIC,SLNAC1,TNaC1,Neuroscience,ASIC3

Molecular Weight: 44 kDa/58 kDa/60 kDa

Gene ID: 9311

UniProt: Q9UHC3