TRIM25 antibody (AA 100-400)

Catalog No. ABIN6149513

Product Details anti-TRIM25 Antibody

Target: TRIM25 (Tripartite Motif Containing 25 (TRIM25))

Binding Specificity: AA 100-400

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRIM25 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)

Sequence: SPNAQVACDH CLKEAAVKTC LVCMASFCQE HLQPHFDSPA FQDHPLQPPV RDLLRRKCSQ HNRLREFFCP EHSECICHIC LVEHKTCSPA SLSQASADLE ATLRHKLTVM YSQINGASRA LDDVRNRQQD VRMTANRKVE QLQQEYTEMK ALLDASETTS TRKIKEEEKR VNSKFDTIYQ ILLKKKSEIQ TLKEEIEQSL TKRDEFEFLE KASKLRGIST KPVYIPEVEL NHKLIKGIHQ STIDLKNELK QCIGRLQEPT PSSGDPGEHD PASTHKSTRP VKKVSKEEKK SKKPPPVPAL P

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 100-400 of human TRIM25 (NP_005073.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200,IP,1:50 - 1:200

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

References for anti-TRIM25 antibody (ABIN6149513)

Lian, Zang, Wei, Ye, Hu, Chen, Zhang, Guo, Lei, Yang, Luo, Li, Shu: "The Zinc-Finger Protein ZCCHC3 Binds RNA and Facilitates Viral RNA Sensing and Activation of the RIG-I-like Receptors." in: Immunity, Vol. 49, Issue 3, pp. 438-448.e5, (2018) (PubMed).

Target Details for TRIM25

Target: TRIM25 (Tripartite Motif Containing 25 (TRIM25))

Alternative Name: TRIM25 (TRIM25 Products)

Synonyms: zgc:55773 antibody, MGC130751 antibody, EFP antibody, RNF147 antibody, Z147 antibody, ZNF147 antibody, AA960166 antibody, AL022677 antibody, Zfp147 antibody, Efp antibody, Znf147 antibody, E3 ubiquitin/ISG15 ligase TRIM25 antibody, tripartite motif containing 25 antibody, E3 ubiquitin/ISG15 ligase TRIM25-like L homeolog antibody, microRNA 3614 antibody, tripartite motif-containing 25 antibody, LOC100146440 antibody, trim25 antibody, LOC100490741.L antibody, TRIM25 antibody, MIR3614 antibody, Trim25 antibody

Background: The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to the cytoplasm. The presence of potential DNA-binding and dimerization-transactivation domains suggests that this protein may act as a transcription factor, similar to several other members of the TRIM family. Expression of the gene is upregulated in response to estrogen, and it is thought to mediate estrogen actions in breast cancer as a primary response gene.,TRIM25,EFP,RNF147,Z147,ZNF147,Epigenetics & Nuclear Signaling,RNA Binding,Signal Transduction,Cell Biology & Developmental Biology,Growth factor,Ubiquitin,TRIM25

Molecular Weight: 70 kDa

Gene ID: 7706

UniProt: Q14258