LKB1 antibody (pThr189)
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- Target See all LKB1 (STK11) Antibodies
- LKB1 (STK11) (serine/threonine Kinase 11 (STK11))
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Binding Specificity
- pThr189
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This LKB1 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- GGTLK
- Cross-Reactivity
- Human, Mouse, Rat
- Characteristics
- Phosphorylated Antibodies
- Immunogen
- A synthetic phosphorylated peptide around T189 of human STK11 (NP_000446.1).
- Isotype
- IgG
- Top Product
- Discover our top product STK11 Primary Antibody
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- Application Notes
- WB,1:500 - 1:2000
- Comment
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HIGH QUALITY
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- LKB1 (STK11) (serine/threonine Kinase 11 (STK11))
- Alternative Name
- STK11 (STK11 Products)
- Synonyms
- pjs antibody, LKB1 antibody, XEEK1 antibody, Stk11 antibody, PJS antibody, hLKB1 antibody, AA408040 antibody, Lkb1 antibody, Par-4 antibody, R75140 antibody, mLKB1 antibody, wu:fj61a05 antibody, zgc:110180 antibody, xeek1 antibody, serine/threonine kinase 11 antibody, polarization-related protein LKB1 antibody, serine/threonine kinase 11 L homeolog antibody, STK11 antibody, stk11 antibody, LOC662493 antibody, Stk11 antibody, stk11.L antibody
- Background
- This gene, which encodes a member of the serine/threonine kinase family, regulates cell polarity and functions as a tumor suppressor. Mutations in this gene have been associated with Peutz-Jeghers syndrome, an autosomal dominant disorder characterized by the growth of polyps in the gastrointestinal tract, pigmented macules on the skin and mouth, and other neoplasms. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.,LKB1,PJS,hLKB1,STK11,Epigenetics & Nuclear Signaling,Translation Control,Regulation of eIF4 and p70 S6 Kinase,Cancer,Tumor suppressors,p53 pathway,Signal Transduction,Kinase,Serine/threonine kinases,PI3K-Akt Signaling Pathway,mTOR Signaling Pathway,Cell Biology & Developmental Biology,Apoptosis,Autophagy,Cell Cycle,Cell cycle inhibitors,Endocrine & Metabolism,AMPK Signaling Pathway,Insulin Receptor Signaling Pathway,Warburg Effect,Regulator of mTOR complex function,Protein phosphorylation,STK11
- Molecular Weight
- 45 kDa/48 kDa
- Gene ID
- 6794
- UniProt
- Q15831
- Pathways
- AMPK Signaling, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, Warburg Effect
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