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ASAH1 antibody (AA 140-389)
ASAH1
Reactivity: Human
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-ASAH1 Antibody
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Target
See all ASAH1 Antibodies
ASAH1
(N-Acylsphingosine Amidohydrolase (Acid Ceramidase) 1 (ASAH1))
Binding Specificity
All epitopes for ASAH1 antibodies
AA 140-389
Reactivity
All reactivities for ASAH1 antibodies
Human
Host
All hosts for ASAH1 antibodies
Rabbit
Clonality
All clonalities for ASAH1 antibodies
Polyclonal
Conjugate
All conjugates for ASAH1 antibodies
This ASAH1 antibody is un-conjugated
Application
All applications for ASAH1 antibodies
Western Blotting (WB)
Sequence
IVAEDKKGHL IHGRNMDFGV FLGWNINNDT WVITEQLKPL TVNLDFQRNN KTVFKASSFA GYVGMLTGFK PGLFSLTLNE RFSINGGYLG ILEWILGKKD VMWIGFLTRT VLENSTSYEE AKNLLTKTKI LAPAYFILGG NQSGEGCVIT RDRKESLDVY ELDAKQGRWY VVQTNYDRWK HPFFLDDRRT PAKMCLNRTS QENISFETMY DVLSTKPVLN KLTVYTTLID VTKGQFETYL RDCPDPCIGW
Cross-Reactivity
Human, Mouse, Rat
Characteristics
Polyclonal Antibodies
Purification
Affinity purification
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 140-389 of human ASAH1 (NP_001120977.1).
Isotype
IgG
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Discover our top product ASAH1 Primary Antibody
Alternatives
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anti-N-Acylsphingosine Amidohydrolase (Acid Ceramidase) 1 (ASAH1) (N-Term) antibody
ASAH1
Reactivity: Human, Mouse, Rat, Dog, Guinea Pig, Horse, Cow, Bat, Hamster, Monkey
WB, IHC, IHC (p)
Host: Rabbit
Polyclonal
unconjugated
Application Details
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Application Notes
WB,1:500 - 1:2000
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Store at -20°C. Avoid freeze / thaw cycles.
Target Details for ASAH1
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Target
ASAH1
(N-Acylsphingosine Amidohydrolase (Acid Ceramidase) 1 (ASAH1))
Alternative Name
ASAH1 (ASAH1 Products )
Synonyms
AC antibody, ACDase antibody, ASAH antibody, PHP antibody, PHP32 antibody, SMAPME antibody, 2310081N20Rik antibody, Asah antibody, MGC82286 antibody, asah1 antibody, zgc:101637 antibody, ASAH1 antibody, zgc:66026 antibody, N-acylsphingosine amidohydrolase 1 antibody, N-acylsphingosine amidohydrolase (acid ceramidase) 1 antibody, N-acylsphingosine amidohydrolase (acid ceramidase) 1 L homeolog antibody, N-acylsphingosine amidohydrolase (acid ceramidase) 1a antibody, Acid ceramidase antibody, N-acylsphingosine amidohydrolase (acid ceramidase) 1b antibody, ASAH1 antibody, Asah1 antibody, asah1.L antibody, asah1a antibody, asah-1 antibody, asah1b antibody
Background
This gene encodes a member of the acid ceramidase family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed. Processing of this preproprotein generates alpha and beta subunits that heterodimerize to form the mature lysosomal enzyme, which catalyzes the degradation of ceramide into sphingosine and free fatty acid. This enzyme is overexpressed in multiple human cancers and may play a role in cancer progression. Mutations in this gene are associated with the lysosomal storage disorder, Farber lipogranulomatosis, and a neuromuscular disorder, spinal muscular atrophy with progressive myoclonic epilepsy.,ASAH1,AC,ACDase,ASAH,PHP,PHP32,SMAPME,Cancer,Signal Transduction,Endocrine & Metabolism,Lipid Metabolism,ASAH1
Molecular Weight
44 kDa/46 kDa
Gene ID
427
UniProt
Q13510
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