CA8 antibody (AA 1-290)
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- Target See all CA8 Antibodies
- CA8 (Carbonic Anhydrase VIII (CA8))
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Binding Specificity
- AA 1-290
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This CA8 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Sequence
- MADLSFIEDT VAFPEKEEDE EEEEEGVEWG YEEGVEWGLV FPDANGEYQS PINLNSREAR YDPSLLDVRL SPNYVVCRDC EVTNDGHTIQ VILKSKSVLS GGPLPQGHEF ELYEVRFHWG RENQRGSEHT VNFKAFPMEL HLIHWNSTLF GSIDEAVGKP HGIAIIALFV QIGKEHVGLK AVTEILQDIQ YKGKSKTIPC FNPNTLLPDP LLRDYWVYEG SLTIPPCSEG VTWILFRYPL TISQLQIEEF RRLRTHVKGA ELVEGCDGIL GDNFRPTQPL SDRVIRAAFQ
- Cross-Reactivity
- Human, Mouse
- Characteristics
- Polyclonal Antibodies
- Purification
- Affinity purification
- Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 1-290 of human CA8 (NP_004047.3).
- Isotype
- IgG
- Top Product
- Discover our top product CA8 Primary Antibody
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- Application Notes
- WB,1:500 - 1:2000,IHC,1:50 - 1:200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- CA8 (Carbonic Anhydrase VIII (CA8))
- Alternative Name
- CA8 (CA8 Products)
- Synonyms
- AW546993 antibody, Ca8 antibody, Cals antibody, Cals1 antibody, Carp antibody, wdl antibody, zgc:110118 antibody, CA-VIII antibody, CALS antibody, CAMRQ3 antibody, CARP antibody, carbonic anhydrase 8 antibody, carbonic anhydrase VIII antibody, CAH8 antibody, Car8 antibody, ca8 antibody, CA8 antibody
- Background
- The protein encoded by this gene was initially named CA-related protein because of sequence similarity to other known carbonic anhydrase genes. However, the gene product lacks carbonic anhydrase activity (i.e., the reversible hydration of carbon dioxide). The gene product continues to carry a carbonic anhydrase designation based on clear sequence identity to other members of the carbonic anhydrase gene family. The absence of CA8 gene transcription in the cerebellum of the lurcher mutant in mice with a neurologic defect suggests an important role for this acatalytic form. Mutations in this gene are associated with cerebellar ataxia, mental retardation, and dysequilibrium syndrome 3 (CMARQ3). Polymorphisms in this gene are associated with osteoporosis, and overexpression of this gene in osteosarcoma cells suggests an oncogenic role. Alternative splicing results in multiple transcript variants.,CA8,CA-RP,CA-VIII,CALS,CAMRQ3,CARP,Cancer,Tumor biomarkers,CA8
- Molecular Weight
- 32 kDa
- Gene ID
- 767
- UniProt
- P35219
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