CYP26B1 antibody (AA 213-512)

Catalog No. ABIN6139325

Product Details anti-CYP26B1 Antibody

Target: CYP26B1 (Cytochrome P450, Family 26, Subfamily B, Polypeptide 1 (CYP26B1))

Binding Specificity: AA 213-512

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CYP26B1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: VYQQFVDNVF SLPVDLPFSG YRRGIQARQI LQKGLEKAIR EKLQCTQGKD YLDALDLLIE SSKEHGKEMT MQELKDGTLE LIFAAYATTA SASTSLIMQL LKHPTVLEKL RDELRAHGIL HSGGCPCEGT LRLDTLSGLR YLDCVIKEVM RLFTPISGGY RTVLQTFELD GFQIPKGWSV MYSIRDTHDT APVFKDVNVF DPDRFSQARS EDKDGRFHYL PFGGGVRTCL GKHLAKLFLK VLAVELASTS RFELATRTFP RITLVPVLHP VDGLSVKFFG LDSNQNEILP ETEAMLSATV

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 213-512 of human CYP26B1 (NP_063938.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for CYP26B1

Target: CYP26B1 (Cytochrome P450, Family 26, Subfamily B, Polypeptide 1 (CYP26B1))

Alternative Name: CYP26B1 (CYP26B1 Products)

Synonyms: cyp26b1 antibody, cyp26a2 antibody, p450rai-2 antibody, CYP26A2 antibody, P450RAI-2 antibody, P450RAI2 antibody, RHFCA antibody, CP26 antibody, fc21d03 antibody, wu:fc21d03 antibody, wu:fc26h10 antibody, zgc:76999 antibody, cytochrome P450 26B1 antibody, cytochrome P450 family 26 subfamily B member 1 L homeolog antibody, cytochrome P450 family 26 subfamily B member 1 antibody, cytochrome P450, family 26, subfamily B, polypeptide 1 antibody, cytochrome P450, family 26, subfamily b, polypeptide 1 antibody, CpipJ_CPIJ002537 antibody, cyp26b1.L antibody, CYP26B1 antibody, cyp26b1 antibody, Cyp26b1 antibody

Background: This gene encodes a member of the cytochrome P450 superfamily. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The encoded protein is localized to the endoplasmic reticulum, and functions as a critical regulator of all-trans retinoic acid levels by the specific inactivation of all-trans retinoic acid to hydroxylated forms. Mutations in this gene are associated with radiohumeral fusions and other skeletal and craniofacial anomalies, and increased levels of the encoded protein are associated with atherosclerotic lesions. Alternative splicing results in multiple transcript variants.,CYP26B1,CYP26A2,P450RAI-2,P450RAI2,RHFCA,Cancer,Signal Transduction,Endocrine & Metabolism,Mitochondrial metabolism,Cytochromes,Lipid Metabolism,Cytochromes,Lipases,Drug metabolism,Immunology & Inflammation,Cytokines,Cardiovascular,Lipids,CYP26B1

Molecular Weight: 49 kDa/55 kDa/57 kDa

Gene ID: 56603

UniProt: Q9NR63

Pathways: Retinoic Acid Receptor Signaling Pathway, Regulation of Muscle Cell Differentiation, Monocarboxylic Acid Catabolic Process