F2RL1 antibody (AA 318-397)

Catalog No. ABIN6224794

Product Details anti-F2RL1 Antibody

Target: F2RL1 (Coagulation Factor II (thrombin) Receptor-Like 1 (F2RL1))

Binding Specificity: AA 318-397

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This F2RL1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Sequence: GQSHVYALYI VALCLSTLNS CIDPFVYYFV SHDFRDHAKN ALLCRSVRTV KQMQVSLTSK KHSRKSSSYS SSSTTVKTSY

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 318-397 of human PAR2 (NP_005233.3).

Isotype: IgG

Application Details

Application Notes: WB,1:200 - 1:1000,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for F2RL1

Target: F2RL1 (Coagulation Factor II (thrombin) Receptor-Like 1 (F2RL1))

Alternative Name: F2RL1 (F2RL1 Products)

Synonyms: par2 antibody, GPR11 antibody, PAR2 antibody, Gpcr11 antibody, PAR-2 antibody, Par2 antibody, Par-2 antibody, Proteinase-activated receptor 2 antibody, F2R like trypsin receptor 1 antibody, coagulation factor II (thrombin) receptor-like 1 antibody, par2 antibody, F2RL1 antibody, F2rl1 antibody

Background: Coagulation factor II (thrombin) receptor-like 1 (F2RL1) is a member of the large family of 7-transmembrane-region receptors that couple to guanosine-nucleotide-binding proteins. F2RL1 is also a member of the protease-activated receptor family. It is activated by trypsin, but not by thrombin. It is activated by proteolytic cleavage of its extracellular amino terminus. The new amino terminus functions as a tethered ligand and activates the receptor. The F2RL1 gene contains two exons and is widely expressed in human tissues. The predicted protein sequence is 83 % identical to the mouse receptor sequence.,F2RL1,GPR11,PAR2,Signal Transduction,G protein signaling,G-Protein-Coupled Receptors(GPCR),F2RL1

Molecular Weight: 44 kDa

Gene ID: 2150

UniProt: P55085

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, SARS-CoV-2 Protein Interactome