CD103 antibody (AA 19-200)

Catalog No. ABIN6142574

Product Details anti-CD103 Antibody

Target: CD103 (ITGAE) (Integrin, alpha E (Antigen CD103, Human Mucosal Lymphocyte Antigen 1, alpha Polypeptide) (ITGAE))

Binding Specificity: AA 19-200

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CD103 antibody is un-conjugated

Application: Immunohistochemistry (IHC), Western Blotting (WB)

Sequence: FNVDVARPWL TPKGGAPFVL SSLLHQDPST NQTWLLVTSP RTKRTPGPLH RCSLVQDEIL CHPVEHVPIP KGRHRGVTVV RSHHGVLICI QVLVRRPHSL SSELTGTCSL LGPDLRPQAQ ANFFDLENLL DPDARVDTGD CYSNKEGGGE DDVNTARQRR ALEKEEEEDK EEEEDEEEEE AG

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 19-200 of human ITGAE (NP_002199.3).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for CD103

Target: CD103 (ITGAE) (Integrin, alpha E (Antigen CD103, Human Mucosal Lymphocyte Antigen 1, alpha Polypeptide) (ITGAE))

Alternative Name: ITGAE (ITGAE Products)

Synonyms: A530055J10 antibody, CD103 antibody, aM290 antibody, alpha-E1 antibody, alpha-M290 antibody, HUMINAE antibody, integrin alpha E, epithelial-associated antibody, integrin subunit alpha E antibody, Itgae antibody, ITGAE antibody

Background: Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This gene encodes an I-domain-containing alpha integrin that undergoes post-translational cleavage in the extracellular domain, yielding disulfide-linked heavy and light chains. In combination with the beta 7 integrin, this protein forms the E-cadherin binding integrin known as the human mucosal lymphocyte-1 antigen. This protein is preferentially expressed in human intestinal intraepithelial lymphocytes (IEL), and in addition to a role in adhesion, it may serve as an accessory molecule for IEL activation.,ITGAE,CD103,HUMINAE,Signal Transduction,PI3K-Akt Signaling Pathway,MAPK-Erk Signaling Pathway,Cell Biology & Developmental Biology,Cell Adhesion,Cytoskeleton,Immunology & Inflammation,CD markers,Stem Cells,Hematopoietic Progenitors,ITGAE

Molecular Weight: 130 kDa

Gene ID: 3682

UniProt: P38570