KPNA6 antibody (AA 277-536)

Catalog No. ABIN6142995

Product Details anti-KPNA6 Antibody

Target: KPNA6 (Karyopherin alpha 6 (Importin alpha 7) (KPNA6))

Binding Specificity: AA 277-536

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KPNA6 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: SYLSDGPNEK IQAVIDSGVC RRLVELLMHN DYKVASPALR AVGNIVTGDD IQTQVILNCS ALPCLLHLLS SPKESIRKEA CWTISNITAG NRAQIQAVID ANIFPVLIEI LQKAEFRTRK EAAWAITNAT SGGTPEQIRY LVSLGCIKPL CDLLTVMDSK IVQVALNGLE NILRLGEQEG KRSGSGVNPY CGLIEEAYGL DKIEFLQSHE NQEIYQKAFD LIEHYFGVED DDSSLAPQVD ETQQQFIFQQ PEAPMEGFQL

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 277-536 of human KPNA6 (NP_036448.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for KPNA6

Target: KPNA6 (Karyopherin alpha 6 (Importin alpha 7) (KPNA6))

Alternative Name: KPNA6 (KPNA6 Products)

Synonyms: IPOA7 antibody, Kpna5 antibody, NPI-2 antibody, KPNA7 antibody, karyopherin subunit alpha 6 antibody, karyopherin (importin) alpha 6 antibody, karyopherin alpha 6 (importin alpha 7) antibody, karyopherin alpha 6 (importin alpha 7) S homeolog antibody, KPNA6 antibody, Kpna6 antibody, kpna6.S antibody

Background: Nucleocytoplasmic transport, a signal- and energy-dependent process, takes place through nuclear pore complexes embedded in the nuclear envelope. The import of proteins containing a nuclear localization signal (NLS) requires the NLS import receptor, a heterodimer of importin alpha and beta subunits also known as karyopherins. Importin alpha binds the NLS-containing cargo in the cytoplasm and importin beta docks the complex at the cytoplasmic side of the nuclear pore complex. In the presence of nucleoside triphosphates and the small GTP binding protein Ran, the complex moves into the nuclear pore complex and the importin subunits dissociate. Importin alpha enters the nucleoplasm with its passenger protein and importin beta remains at the pore. The protein encoded by this gene is a member of the importin alpha family.,KPNA6,IPOA7,KPNA7,Signal Transduction,KPNA6

Molecular Weight: 60 kDa

Gene ID: 23633

UniProt: O60684

Pathways: Protein targeting to Nucleus