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KRT6A antibody (AA 305-564)

KRT6A Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6143033
  • Target See all KRT6A Antibodies
    KRT6A (Keratin 6A (KRT6A))
    Binding Specificity
    • 9
    • 7
    • 7
    • 6
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 305-564
    Reactivity
    • 62
    • 21
    • 11
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 60
    • 14
    • 1
    Rabbit
    Clonality
    • 59
    • 16
    Polyclonal
    Conjugate
    • 36
    • 12
    • 9
    • 6
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This KRT6A antibody is un-conjugated
    Application
    • 55
    • 38
    • 26
    • 5
    • 5
    • 5
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB)
    Sequence
    ELSQMQTHIS DTSVVLSMDN NRNLDLDSII AEVKAQYEEI AQRSRAEAES WYQTKYEELQ VTAGRHGDDL RNTKQEIAEI NRMIQRLRSE IDHVKKQCAN LQAAIADAEQ RGEMALKDAK NKLEGLEDAL QKAKQDLARL LKEYQELMNV KLALDVEIAT YRKLLEGEEC RLNGEGVGQV NISVVQSTVS SGYGGASGVG SGLGLGGGSS YSYGSGLGVG GGFSSSSGRA IGGGLSSVGG GSSTIKYTTT SSSSRKSYKH
    Cross-Reactivity
    Human
    Characteristics
    Polyclonal Antibodies
    Immunogen
    Recombinant fusion protein containing a sequence corresponding to amino acids 305-564 of human Cytokeratin 6 (KRT6) (NP_005545.1).
    Isotype
    IgG
    Top Product
    Discover our top product KRT6A Primary Antibody
  • Application Notes
    WB,1:500 - 1:2000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    KRT6A (Keratin 6A (KRT6A))
    Alternative Name
    KRT6A (KRT6A Products)
    Synonyms
    CK6A antibody, CK6C antibody, CK6D antibody, K6A antibody, K6C antibody, K6D antibody, KRT6C antibody, KRT6D antibody, 2310016L08Rik antibody, Krt2-6a antibody, Krt2-6c antibody, MK6a antibody, mK6[a] antibody, CK-6A antibody, Krt6a antibody, KRT6A antibody, keratin 6A antibody, similar to keratin complex 2, basic, gene 6a antibody, keratin, type II cytoskeletal 6A antibody, KRT6A antibody, Krt6a antibody, LOC683313 antibody, LOC101112304 antibody
    Background
    The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. As many as six of this type II cytokeratin (KRT6) have been identified, the multiplicity of the genes is attributed to successive gene duplication events. The genes are expressed with family members KRT16 and/or KRT17 in the filiform papillae of the tongue, the stratified epithelial lining of oral mucosa and esophagus, the outer root sheath of hair follicles, and the glandular epithelia. This KRT6 gene in particular encodes the most abundant isoform. Mutations in these genes have been associated with pachyonychia congenita. In addition, peptides from the C-terminal region of the protein have antimicrobial activity against bacterial pathogens. The type II cytokeratins are clustered in a region of chromosome 12q12-q13.,KRT6A,CK-6C,CK-6E,CK6A,CK6C,CK6D,K6A,K6C,K6D,KRT6C,KRT6D,PC3,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Intermediate Filaments,Extracellular Matrix,Cytokeratin,Keratin,KRT6A
    Molecular Weight
    60 kDa
    Gene ID
    3853
    UniProt
    P02538
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