Keratin 6B antibody (AA 1-280)

Catalog No. ABIN6143035

Product Details anti-Keratin 6B Antibody

Target: Keratin 6B (KRT6B)

Binding Specificity: AA 1-280

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Keratin 6B antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: MASTSTTIRS HSSSRRGFSA NSARLPGVSR SGFSSISVSR SRGSGGLGGA CGGAGFGSRS LYGLGGSKRI SIGGGSCAIS GGYGSRAGGS YGFGGAGSGF GFGGGAGIGF GLGGGAGLAG GFGGPGFPVC PPGGIQEVTV NQSLLTPLNL QIDPAIQRVR AEEREQIKTL NNKFASFIDK VRFLEQQNKV LDTKWTLLQE QGTKTVRQNL EPLFEQYINN LRRQLDNIVG ERGRLDSELR NMQDLVEDLK NKYEDEINKR TAAENEFVTL KKDVDAAYMN

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human KRT6B (NP_005546.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Keratin 6B

Target: Keratin 6B (KRT6B)

Alternative Name: KRT6B (KRT6B Products)

Synonyms: CK-6B antibody, CK6B antibody, K6B antibody, KRTL1 antibody, PC2 antibody, KRT6C antibody, KRT6A antibody, KRT6B antibody, BB144589 antibody, Krt2-6b antibody, mK6[b] antibody, KERIV antibody, keratin 6B antibody, keratin, type II cytoskeletal 5 antibody, keratin, type II cytoskeletal 6B antibody, KRT6B antibody, Krt6b antibody, LOC100566088 antibody, LOC100593588 antibody

Background: The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. As many as six of this type II cytokeratin (KRT6) have been identified, the multiplicity of the genes is attributed to successive gene duplication events. The genes are expressed with family members KRT16 and/or KRT17 in the filiform papillae of the tongue, the stratified epithelial lining of oral mucosa and esophagus, the outer root sheath of hair follicles, and the glandular epithelia. Mutations in these genes have been associated with pachyonychia congenita. The type II cytokeratins are clustered in a region of chromosome 12q12-q13.,KRT6B,CK-6B,CK6B,K6B,KRTL1,PC2,PC4,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Intermediate Filaments,Extracellular Matrix,Cytokeratin,Keratin,KRT6B

Molecular Weight: 60 kDa

Gene ID: 3854

UniProt: P04259