MDH1 antibody (AA 1-334)

Catalog No. ABIN6143665

Product Details anti-MDH1 Antibody

Target: MDH1 (Malate Dehydrogenase 1, NAD (Soluble) (MDH1))

Binding Specificity: AA 1-334

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MDH1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: MSEPIRVLVT GAAGQIAYSL LYSIGNGSVF GKDQPIILVL LDITPMMGVL DGVLMELQDC ALPLLKDVIA TDKEDVAFKD LDVAILVGSM PRREGMERKD LLKANVKIFK SQGAALDKYA KKSVKVIVVG NPANTNCLTA SKSAPSIPKE NFSCLTRLDH NRAKAQIALK LGVTANDVKN VIIWGNHSST QYPDVNHAKV KLQGKEVGVY EALKDDSWLK GEFVTTVQQR GAAVIKARKL SSAMSAAKAI CDHVRDIWFG TPEGEFVSMG VISDGNSYGV PDDLLYSFPV VIKNKTWKFV EGLPINDFSR EKMDLTAKEL TEEKESAFEF LSSA

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-334 of human MDH1 (NP_005908.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for MDH1

Target: MDH1 (Malate Dehydrogenase 1, NAD (Soluble) (MDH1))

Alternative Name: MDH1 (MDH1 Products)

Synonyms: MDH-s antibody, MDHA antibody, MGC:1375 antibody, MOR2 antibody, ODS1 antibody, B230377B03Rik antibody, D17921 antibody, Mor-2 antibody, Mor2 antibody, MDL1 antibody, Mdhl antibody, MDH antibody, mdh-s antibody, mdha antibody, mor2 antibody, MDH-1 antibody, Mdh antibody, Mdh-1 antibody, Mdh2 antibody, MdhD antibody, cMdh antibody, sMdh antibody, malate dehydrogenase 1 antibody, malic enzyme 2 antibody, malate dehydrogenase 1, NAD (soluble) antibody, malate dehydrogenase 1 S homeolog antibody, malate dehydrogenase, cytoplasmic antibody, Malate dehydrogenase 1 antibody, MDH1 antibody, ME2 antibody, Mdh1 antibody, mdh1.S antibody, LOC100280767 antibody

Background: This gene encodes an enzyme that catalyzes the NAD/NADH-dependent, reversible oxidation of malate to oxaloacetate in many metabolic pathways, including the citric acid cycle. Two main isozymes are known to exist in eukaryotic cells: one is found in the mitochondrial matrix and the other in the cytoplasm. This gene encodes the cytosolic isozyme, which plays a key role in the malate-aspartate shuttle that allows malate to pass through the mitochondrial membrane to be transformed into oxaloacetate for further cellular processes. Alternatively spliced transcript variants have been found for this gene. A recent study showed that a C-terminally extended isoform is produced by use of an alternative in-frame translation termination codon via a stop codon readthrough mechanism, and that this isoform is localized in the peroxisomes. Pseudogenes have been identified on chromosomes X and 6.,MDH1,HEL-S-32,MDH-s,MDHA,MGC:1375,MOR2,Cancer,Signal Transduction,Endocrine & Metabolism,Carbohydrate metabolism,MDH1

Molecular Weight: 27 kDa/36 kDa/38 kDa

Gene ID: 4190

UniProt: P40925