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MR1 antibody (AA 20-260)

MR1 Reactivity: Human WB, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6143983
  • Target See all MR1 Antibodies
    MR1 (Major Histocompatibility Complex, Class I-Related (MR1))
    Binding Specificity
    • 11
    • 8
    • 6
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 20-260
    Reactivity
    • 34
    • 2
    • 1
    Human
    Host
    • 30
    • 4
    Rabbit
    Clonality
    • 31
    • 3
    Polyclonal
    Conjugate
    • 14
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MR1 antibody is un-conjugated
    Application
    • 23
    • 23
    • 4
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    Sequence
    SDSRTHSLRY FRLGVSDPIH GVPEFISVGY VDSHPITTYD SVTRQKEPRA PWMAENLAPD HWERYTQLLR GWQQMFKVEL KRLQRHYNHS DNVAHTIKQA WEANQHELLY QKNWLEEECI AWLKRFLEYG KDTLQRTEPP LVRVNRKETF PGVTALFCKA HGFYPPEIYM TWMKNGEEIV QEIDYGDILP SGDGTYQAWA SIELDPQSSN LYSCHVEHCG VHMVLQVPQE SETIPLVMKA V
    Cross-Reactivity
    Human, Mouse, Rat
    Characteristics
    Polyclonal Antibodies
    Immunogen
    Recombinant fusion protein containing a sequence corresponding to amino acids 20-260 of human MR1 (NP_001181928.1).
    Isotype
    IgG
    Top Product
    Discover our top product MR1 Primary Antibody
  • Application Notes
    WB,1:500 - 1:2000,IF,1:50 - 1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    MR1 (Major Histocompatibility Complex, Class I-Related (MR1))
    Alternative Name
    MR1 (MR1 Products)
    Synonyms
    YFV antibody, hlals antibody, MGC154362 antibody, MR1 antibody, DKFZp468C1823 antibody, HLALS antibody, H2ls antibody, Hlals antibody, MHC class I antigen YF5 antibody, major histocompatibility complex, class I-related antibody, major histocompatibility complex, class I-related L homeolog antibody, YF5 antibody, MR1 antibody, mr1.L antibody, mr1 antibody, Mr1 antibody
    Background
    MAIT (mucosal-associated invariant T-cells) lymphocytes represent a small population of T-cells primarily found in the gut. The protein encoded by this gene is an antigen-presenting molecule that presents metabolites of microbial vitamin B to MAITs. This presentation may activate the MAITs to regulate the amounts of specific types of bacteria in the gut. Several transcript variants encoding different isoforms have been found for this gene, and a pseudogene of it has been detected about 36 kbp upstream on the same chromosome.,MR1,HLALS,Immunology & Inflammation,MR1
    Molecular Weight
    25 kDa/28 kDa/34 kDa/39 kDa
    Gene ID
    3140
    UniProt
    Q95460
    Pathways
    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints
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