NPHP3 antibody (AA 1-130)

Catalog No. ABIN6144770

Product Details anti-NPHP3 Antibody

Target: NPHP3 (Nephronophthisis 3 (Adolescent) (NPHP3))

Binding Specificity: AA 1-130

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NPHP3 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: MGTASSLVSP AGGEVIEDTY GAGGGEACEI PVEVKPKARL LRNSFRRGAG AAAGAGPGSL PRGVGAGGLL GASFKSTGSS VPELEYAAAE YERLRKEYEI FRVSKNQELL SMGRREAKLD TENKRLRAEL

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-130 of human NPHP3 (NP_694972.3).

Isotype: IgG

Application Details

Application Notes: WB,1:200 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for NPHP3

Target: NPHP3 (Nephronophthisis 3 (Adolescent) (NPHP3))

Alternative Name: NPHP3 (NPHP3 Products)

Synonyms: si:dkey-56l10.1 antibody, MKS7 antibody, NPH3 antibody, RHPD antibody, 3632410F03Rik antibody, AI550417 antibody, C230078J01 antibody, D330020E01Rik antibody, pcy antibody, RGD1563856 antibody, nephronophthisis 3 antibody, nephrocystin 3 antibody, nephronophthisis 3 (adolescent) antibody, nphp3 antibody, NPHP3 antibody, Nphp3 antibody

Background: This gene encodes a protein containing a coiled-coil (CC) domain, a tubulin-tyrosine ligase (TTL) domain, and a tetratrico peptide repeat (TPR) domain. The encoded protein interacts with nephrocystin, it is required for normal ciliary development, and it functions in renal tubular development. Mutations in this gene are associated with nephronophthisis type 3, and also with renal-hepatic-pancreatic dysplasia, and Meckel syndrome type 7. Naturally occurring read-through transcripts exist between this gene and the downstream ACAD11 (acyl-CoA dehydrogenase family, member 11) gene.,NPHP3,CFAP31,MKS7,NPH3,RHPD,RHPD1,SLSN3,NPHP3

Molecular Weight: 15 kDa/19 kDa/26 kDa/71 kDa/73 kDa/79 kDa/150 kDa

Gene ID: 27031

UniProt: Q7Z494

Pathways: cAMP Metabolic Process