PABPC4 antibody (AA 350-450)
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- Target See all PABPC4 Antibodies
- PABPC4 (Poly(A) Binding Protein, Cytoplasmic 4 (Inducible Form) (PABPC4))
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Binding Specificity
- AA 350-450
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This PABPC4 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
- Sequence
- VTEMNGRIVG SKPLYVALAQ RKEERKAHLT NQYMQRVAGM RALPANAILN QFQPAAGGYF VPAVPQAQGR PPYYTPNQLA QMRPNPRWQQ GGRPQGFQGM P
- Cross-Reactivity
- Human, Mouse, Rat
- Characteristics
- Polyclonal Antibodies
- Immunogen
- A synthetic peptide corresponding to a sequence within amino acids 350-450 of human PABPC4 (NP_003810.1).
- Isotype
- IgG
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- Application Notes
- WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200
- Comment
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HIGH QUALITY
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- PABPC4 (Poly(A) Binding Protein, Cytoplasmic 4 (Inducible Form) (PABPC4))
- Alternative Name
- PABPC4 (PABPC4 Products)
- Synonyms
- cb12 antibody, sb:cb12 antibody, PABP antibody, ePAB antibody, ePABP antibody, APP-1 antibody, APP1 antibody, PABP4 antibody, iPABP antibody, polyadenylate-binding protein 4 antibody, poly(A) binding protein, cytoplasmic 4 antibody, poly(A) binding protein, cytoplasmic 4 (inducible form) antibody, poly(A) binding protein cytoplasmic 4 L homeolog antibody, poly(A) binding protein cytoplasmic 4 antibody, Bm1_06880 antibody, Pabpc4 antibody, pabpc4 antibody, pabpc4.L antibody, PABPC4 antibody
- Background
- Poly(A)-binding proteins (PABPs) bind to the poly(A) tail present at the 3-prime ends of most eukaryotic mRNAs. PABPC4 or IPABP (inducible PABP) was isolated as an activation-induced T-cell mRNA encoding a protein. Activation of T cells increased PABPC4 mRNA levels in T cells approximately 5-fold. PABPC4 contains 4 RNA-binding domains and proline-rich C terminus. PABPC4 is localized primarily to the cytoplasm. It is suggested that PABPC4 might be necessary for regulation of stability of labile mRNA species in activated T cells. PABPC4 was also identified as an antigen, APP1 (activated-platelet protein-1), expressed on thrombin-activated rabbit platelets. PABPC4 may also be involved in the regulation of protein translation in platelets and megakaryocytes or may participate in the binding or stabilization of polyadenylates in platelet dense granules. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.,PABPC4,APP-1,APP1,PABP4,iPABP,Epigenetics & Nuclear Signaling,RNA Binding,PABPC4
- Molecular Weight
- 69 kDa/70 kDa/72 kDa
- Gene ID
- 8761
- UniProt
- Q13310
- Pathways
- SARS-CoV-2 Protein Interactome
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