PAICS antibody (AA 176-425)
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- Target See all PAICS Antibodies
- PAICS (phosphoribosylaminoimidazole Carboxylase, phosphoribosylaminoimidazole Succinocarboxamide Synthetase (PAICS))
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Binding Specificity
- AA 176-425
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This PAICS antibody is un-conjugated
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Application
- Western Blotting (WB), Immunofluorescence (IF)
- Sequence
- LEKSWLPQNC TLVDMKIEFG VDVTTKEIVL ADVIDNDSWR LWPSGDRSQQ KDKQSYRDLK EVTPEGLQMV KKNFEWVAER VELLLKSESQ CRVVVLMGST SDLGHCEKIK KACGNFGIPC ELRVTSAHKG PDETLRIKAE YEGDGIPTVF VAVAGRSNGL GPVMSGNTAY PVISCPPLTP DWGVQDVWSS LRLPSGLGCS TVLSPEGSAQ FAAQIFGLSN HLVWSKLRAS ILNTWISLKQ ADKKIRECNL
- Cross-Reactivity
- Human, Rat
- Characteristics
- Polyclonal Antibodies
- Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 176-425 of human PAICS (NP_001072992.1).
- Isotype
- IgG
- Top Product
- Discover our top product PAICS Primary Antibody
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- Application Notes
- WB,1:500 - 1:2000,IF,1:10 - 1:100
- Comment
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HIGH QUALITY
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- PAICS (phosphoribosylaminoimidazole Carboxylase, phosphoribosylaminoimidazole Succinocarboxamide Synthetase (PAICS))
- Alternative Name
- PAICS (PAICS Products)
- Synonyms
- cb293 antibody, sb:cb293 antibody, wu:fa28a05 antibody, GB14262 antibody, DDBDRAFT_0218550 antibody, DDBDRAFT_0230088 antibody, DDB_0218550 antibody, DDB_0230088 antibody, AIRC antibody, AS antibody, ADE2 antibody, ADE2H1 antibody, PAIS antibody, Ade2h1 antibody, Airc antibody, ade2 antibody, airc antibody, paics antibody, pais antibody, 2610511I09Rik antibody, phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase antibody, phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase antibody, multifunctional protein ADE2 antibody, phosphoribosylaminoimidazole carboxylase antibody, phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase, gene 2 L homeolog antibody, phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoribosylaminoimidazole, succinocarboxamide synthetase antibody, PAICS antibody, paics antibody, LOC551966 antibody, Tsp_02239a antibody, Tsp_02239 antibody, CNE02500 antibody, purC/E antibody, Paics antibody, paics.2.L antibody
- Background
- This gene encodes a bifunctional enzyme containing phosphoribosylaminoimidazole carboxylase activity in its N-terminal region and phosphoribosylaminoimidazole succinocarboxamide synthetase in its C-terminal region. It catalyzes steps 6 and 7 of purine biosynthesis. The gene is closely linked and divergently transcribed with a locus that encodes an enzyme in the same pathway, and transcription of the two genes is coordinately regulated. The human genome contains several pseudogenes of this gene. Multiple transcript variants encoding different isoforms have been found for this gene.,PAICS,ADE2,ADE2H1,AIRC,PAIS,Epigenetics & Nuclear Signaling,Signal Transduction,Endocrine & Metabolism,Nucleotide metabolism,PAICS
- Molecular Weight
- 47 kDa
- Gene ID
- 10606
- UniProt
- P22234
- Pathways
- Chromatin Binding
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