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PDE6A antibody (AA 656-860)
PDE6A
Reactivity: Human
WB, IHC
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-PDE6A Antibody
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Target
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PDE6A
(phosphodiesterase 6A, CGMP-Specific, Rod, alpha (PDE6A))
Binding Specificity
All epitopes for PDE6A antibodies
AA 656-860
Reactivity
All reactivities for PDE6A antibodies
Human
Host
All hosts for PDE6A antibodies
Rabbit
Clonality
All clonalities for PDE6A antibodies
Polyclonal
Conjugate
All conjugates for PDE6A antibodies
This PDE6A antibody is un-conjugated
Application
All applications for PDE6A antibodies
Western Blotting (WB), Immunohistochemistry (IHC)
Sequence
EHAIHMMDIA IIATDLALYF KKRTMFQKIV DQSKTYESEQ EWTQYMMLEQ TRKEIVMAMM MTACDLSAIT KPWEVQSQVA LLVAAEFWEQ GDLERTVLQQ NPIPMMDRNK ADELPKLQVG FIDFVCTFVY KEFSRFHEEI TPMLDGITNN RKEWKALADE YDAKMKVQEE KKQKQQSAKS AAAGNQPGGN PSPGGATTSK SCCIQ
Cross-Reactivity
Human, Mouse, Rat
Characteristics
Polyclonal Antibodies
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 656-860 of human PDE6A (NP_000431.2).
Isotype
IgG
Top Product
Discover our top product PDE6A Primary Antibody
Alternatives
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anti-phosphodiesterase 6A, CGMP-Specific, Rod, alpha (PDE6A) (AA 99-148) antibody
PDE6A
Reactivity: Human, Mouse, Rat, Hamster, Cow, Dog, Guinea Pig, Horse, Zebrafish (Danio rerio), Bat
WB
Host: Rabbit
Polyclonal
unconjugated
Application Details
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Application Notes
WB,1:500 - 1:2000,IHC,1:50 - 1:200
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Store at -20°C. Avoid freeze / thaw cycles.
Target Details for PDE6A
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Target
PDE6A
(phosphodiesterase 6A, CGMP-Specific, Rod, alpha (PDE6A))
Alternative Name
PDE6A (PDE6A Products )
Synonyms
si:bz1d10.3 antibody, si:rp71-1d10.3 antibody, CGPR-A antibody, PDEA antibody, RP43 antibody, Pdea antibody, nmf282 antibody, phosphodiesterase 6A, cGMP-specific, rod, alpha antibody, phosphodiesterase 6A antibody, pde6a antibody, PDE6A antibody, Pde6a antibody
Background
This gene encodes the cyclic-GMP (cGMP)-specific phosphodiesterase 6A alpha subunit, expressed in cells of the retinal rod outer segment. The phosphodiesterase 6 holoenzyme is a heterotrimer composed of an alpha, beta, and two gamma subunits. cGMP is an important regulator of rod cell membrane current, and its dynamic concentration is established by phosphodiesterase 6A cGMP hydrolysis and guanylate cyclase cGMP synthesis. The protein is a subunit of a key phototransduction enzyme and participates in processes of transmission and amplification of the visual signal. Mutations in this gene have been identified as one cause of autosomal recessive retinitis pigmentosa.,PDE6A,CGPR-A,PDEA,RP43,Signal Transduction,Neuroscience,PDE6A
Molecular Weight
99 kDa
Gene ID
5145
UniProt
P16499
Pathways
Regulation of G-Protein Coupled Receptor Protein Signaling , Phototransduction
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