MSS4 antibody, STM7 antibody, AI844522 antibody, Pip5k1a antibody, Pipk5a antibody, Pipk5b antibody, MGC80809 antibody, pip5k1b antibody, zgc:101046 antibody, wu:fj29b05 antibody, wu:fj93b05 antibody, zgc:92316 antibody, phosphatidylinositol-4-phosphate 5-kinase type 1 beta antibody, phosphatidylinositol-4-phosphate 5-kinase, type 1 beta antibody, phosphatidylinositol-4-phosphate 5-kinase, type I, beta L homeolog antibody, phosphatidylinositol-4-phosphate 5-kinase, type I, beta a antibody, phosphatidylinositol-4-phosphate 5-kinase, type I, beta antibody, phosphatidylinositol 4-phosphate 5-kinase type-1 beta antibody, phosphatidylinositol-4-phosphate 5-kinase, type I, beta b antibody, PIP5K1B antibody, Pip5k1b antibody, pip5k1b.L antibody, pip5k1ba antibody, pip5k1b antibody, LOC100472550 antibody, pip5k1bb antibody
Background
Catalyzes the phosphorylation of phosphatidylinositol 4-phosphate (PtdIns(4P/PI4P to form phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5P2/PIP2, a lipid second messenger that regulates several cellular processes such as signal transduction, vesicle trafficking, actin cytoskeleton dynamics, cell adhesion, and cell motility (By similarity. PtdIns(4,5P2 can directly act as a second messenger or can be utilized as a precursor to generate other second messengers: inositol 1,4,5-trisphosphate (IP3, diacylglycerol (DAG or phosphatidylinositol-3,4,5-trisphosphate (PtdIns(3,4,5P3/PIP3 (By similarity. Mediates RAC1-dependent reorganization of actin filaments. Contributes to the activation of phospholipase PLD2. Together with PIP5K1A, is required, after stimulation by G-protein coupled receptors, for the synthesis of IP3 that will induce stable platelet adhesion (By similarity.,PIP5K1B,MSS4,STM7,Signal Transduction,Kinase,Cell Biology & Developmental Biology,Cytoskeleton,Actins,PIP5K1B