PSMD8 antibody (AA 101-350)

Catalog No. ABIN6146347

Product Details anti-PSMD8 Antibody

Target: PSMD8 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 8 (PSMD8))

Binding Specificity: AA 101-350

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PSMD8 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Sequence: EWNRKSPNLS KCGEELGRLK LVLLELNFLP TTGTKLTKQQ LILARDILEI GAQWSILRKD IPSFERYMAQ LKCYYFDYKE QLPESAYMHQ LLGLNLLFLL SQNRVAEFHT ELERLPAKDI QTNVYIKHPV SLEQYLMEGS YNKVFLAKGN IPAESYTFFI DILLDTIRDE IAGCIEKAYE KILFTEATRI LFFNTPKKMT DYAKKRGWVL GPNNYYSFAS QQQKPEDTTI PSTELAKQVI EYARQLEMIV

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 101-350 of human PSMD8 (NP_002803.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:50 - 1:100

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PSMD8

Target: PSMD8 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 8 (PSMD8))

Alternative Name: PSMD8 (PSMD8 Products)

Synonyms: HIP6 antibody, HYPF antibody, Nin1p antibody, Rpn12 antibody, S14 antibody, p31 antibody, hip6 antibody, hypf antibody, nin1p antibody, rpn12 antibody, psmd8b antibody, 6720456J22Rik antibody, AA407360 antibody, AL033291 antibody, AL033322 antibody, AL033323 antibody, C76433 antibody, psmd8 antibody, psmd8a antibody, fa93g07 antibody, fb17c09 antibody, fb49a10 antibody, zgc:86762 antibody, wu:fa93g07 antibody, wu:fb17c09 antibody, wu:fb49a10 antibody, PSMD8 antibody, proteasome 26S subunit, non-ATPase 8 antibody, proteasome 26S subunit, non-ATPase 8 S homeolog antibody, proteasome (prosome, macropain) 26S subunit, non-ATPase, 8 antibody, proteasome 26S subunit, non-ATPase 8 L homeolog antibody, proteasome (prosome, macropain) 26S subunit, non-ATPase, 8 pseudogene antibody, PSMD8 antibody, psmd8.S antibody, Psmd8 antibody, psmd8.L antibody, psmd8 antibody, LOC468490 antibody

Background: The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. A pseudogene has been identified on chromosome 1.,PSMD8,HEL-S-91n,HIP6,HYPF,Nin1p,Rpn12,S14,p31,Cell Biology & Developmental Biology,Ubiquitin,PSMD8

Molecular Weight: 39 kDa

Gene ID: 5714

UniProt: P48556

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Proton Transport, Synthesis of DNA, SARS-CoV-2 Protein Interactome, Ubiquitin Proteasome Pathway