PVRL2 antibody (AA 382-479)

Catalog No. ABIN6146511

Product Details anti-PVRL2 Antibody

Target: PVRL2 (Poliovirus Receptor-Related 2 (Herpesvirus Entry Mediator B) (PVRL2))

Binding Specificity: AA 382-479

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PVRL2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: FILLRVRRRR KSPGGAGGGA SGDGGFYDPK AQVLGNGDPV FWTPVVPGPM EPDGKDEEEE EEEEKAEKGL MLPPPPALED DMESQLDGSL ISRRAVYV

Cross-Reactivity: Human

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 382-479 of human Nectin 2/CD112 (NP_002847.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PVRL2

Target: PVRL2 (Poliovirus Receptor-Related 2 (Herpesvirus Entry Mediator B) (PVRL2))

Alternative Name: NECTIN2 (PVRL2 Products)

Synonyms: prr2 antibody, AI325026 antibody, AI987993 antibody, Cd112 antibody, MPH antibody, Pvr antibody, Pvs antibody, nectin-2 antibody, CD112 antibody, HVEB antibody, PRR2 antibody, PVRR2 antibody, nectin cell adhesion molecule 2 antibody, Nectin2 antibody, NECTIN2 antibody

Background: This gene encodes a single-pass type I membrane glycoprotein with two Ig-like C2-type domains and an Ig-like V-type domain. This protein is one of the plasma membrane components of adherens junctions. It also serves as an entry for certain mutant strains of herpes simplex virus and pseudorabies virus, and it is involved in cell to cell spreading of these viruses. Variations in this gene have been associated with differences in the severity of multiple sclerosis. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.,NECTIN2,CD112,HVEB,PRR2,PVRL2,PVRR2,nectin-2,Immunology & Inflammation,CD markers,NECTIN2

Molecular Weight: 51 kDa/57 kDa

Gene ID: 5819

UniProt: Q92692

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cell-Cell Junction Organization