SCNN1A antibody (AA 105-225)

Catalog No. ABIN6147447

Product Details anti-SCNN1A Antibody

Target: SCNN1A (Sodium Channel, Nonvoltage-Gated 1 alpha (SCNN1A))

Binding Specificity: AA 105-225

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SCNN1A antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Sequence: LFGEYFSYPV SLNINLNSDK LVFPAVTICT LNPYRYPEIK EELEELDRIT EQTLFDLYKY SSFTTLVAGS RSRRDLRGTL PHPLQRLRVP PPPHGARRAR SVASSLRDNN PQVDWKDWKI G

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 105-225 of human SCNN1A (NP_001029.1).

Isotype: IgG

Application Details

Application Notes: WB,1:200 - 1:2000,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for SCNN1A

Target: SCNN1A (Sodium Channel, Nonvoltage-Gated 1 alpha (SCNN1A))

Alternative Name: SCNN1A (SCNN1A Products)

Synonyms: BESC2 antibody, ENaCa antibody, ENaCalpha antibody, SCNEA antibody, SCNN1 antibody, ENaC antibody, Scnn1 antibody, mENaC antibody, SCNN1A antibody, alphaxENaC antibody, besc2 antibody, enaca antibody, scnn1 antibody, ENAC antibody, sodium channel epithelial 1 alpha subunit antibody, sodium channel, nonvoltage-gated 1 alpha antibody, sodium channel, non voltage gated 1 alpha subunit L homeolog antibody, Scnn1a antibody, SCNN1A antibody, scnn1a.L antibody

Background: Nonvoltage-gated, amiloride-sensitive, sodium channels control fluid and electrolyte transport across epithelia in many organs. These channels are heteromeric complexes consisting of 3 subunits: alpha, beta, and gamma. This gene encodes the alpha subunit, and mutations in this gene have been associated with pseudohypoaldosteronism type 1 (PHA1), a rare salt wasting disease resulting from target organ unresponsiveness to mineralocorticoids. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.,SCNN1A,BESC2,ENaCa,ENaCalpha,SCNEA,SCNN1,Cancer,Signal Transduction,Endocrine & Metabolism,Insulin Receptor Signaling Pathway,Neuroscience,SCNN1A

Molecular Weight: 28 kDa/73 kDa/75 kDa/77 kDa/78 kDa/81 kDa

Gene ID: 6337

UniProt: P37088