P-Selectin antibody (AA 220-319)

Catalog No. ABIN6147501

Product Details anti-P-Selectin Antibody

Target: P-Selectin (SELP) (Selectin P (Granule Membrane Protein 140kDa, Antigen CD62) (SELP))

Binding Specificity: AA 220-319

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This P-Selectin antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: FSFNSQCSFH CTDGYQVNGP SKLECLASGI WTNKPPQCLA AQCPPLKIPE RGNMTCLHSA KAFQHQSSCS FSCEEGFALV GPEVVQCTAS GVWTAPAPVC

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 220-319 of human CD62P/P-selectin (NP_002996.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for P-Selectin

Target: P-Selectin (SELP) (Selectin P (Granule Membrane Protein 140kDa, Antigen CD62) (SELP))

Alternative Name: CD62P/P-selectin (SELP Products)

Synonyms: PSELECT antibody, CD62 antibody, CD62P antibody, GMP140 antibody, GRMP antibody, LECAM3 antibody, PADGEM antibody, PSEL antibody, GMP-140 antibody, Grmp antibody, selectin P antibody, selectin, platelet antibody, Selp antibody, SELP antibody

Background: This gene encodes a 140 kDa protein that is stored in the alpha-granules of platelets and Weibel-Palade bodies of endothelial cells. This protein redistributes to the plasma membrane during platelet activation and degranulation and mediates the interaction of activated endothelial cells or platelets with leukocytes. The membrane protein is a calcium-dependent receptor that binds to sialylated forms of Lewis blood group carbohydrate antigens on neutrophils and monocytes. Alternative splice variants may occur but are not well documented.,SELP,CD62,CD62P,GMP140,GRMP,LECAM3,PADGEM,PSEL,Cell Biology & Developmental Biology,Cell Adhesion,Cell Adhesion Molecules,Immunology & Inflammation,CD markers,Stem Cells,Hematopoietic Progenitors,Cardiovascular,Blood,CD62P/P-selectin

Molecular Weight: 90 kDa

Gene ID: 6403

UniProt: P16109