SPTLC1 antibody (AA 37-310)

Catalog No. ABIN6148409

Product Details anti-SPTLC1 Antibody

Target: SPTLC1 (serine Palmitoyltransferase, Long Chain Base Subunit 1 (SPTLC1))

Binding Specificity: AA 37-310

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SPTLC1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: RLLFSKTYKL QERSDLTVKE KEELIEEWQP EPLVPPVPKD HPALNYNIVS GPPSHKTVVN GKECINFASF NFLGLLDNPR VKAAALASLK KYGVGTCGPR GFYGTFDVHL DLEDRLAKFM KTEEAIIYSY GFATIASAIP AYSKRGDIVF VDRAACFAIQ KGLQASRSDI KLFKHNDMAD LERLLKEQEI EDQKNPRKAR VTRRFIVVEG LYMNTGTICP LPELVKLKYK YKARIFLEES LSFGVLGEHG RGVTEHYGIN IDDIDLISAN MENA

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 37-310 of human SPTLC1 (NP_006406.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for SPTLC1

Target: SPTLC1 (serine Palmitoyltransferase, Long Chain Base Subunit 1 (SPTLC1))

Alternative Name: SPTLC1 (SPTLC1 Products)

Synonyms: ATSPT1 antibody, SERINE PALMITOYLTRANSFERASE 1 antibody, serine palmitoyltransferase 1 antibody, Afu6g00300 antibody, HSAN1 antibody, HSN1 antibody, LBC1 antibody, LCB1 antibody, SPT1 antibody, SPTI antibody, wu:fc75h04 antibody, wu:fp41c08 antibody, zgc:112247 antibody, AW552086 antibody, C77762 antibody, E030036H05 antibody, Lcb1 antibody, RGD1306617 antibody, Spt1 antibody, serine palmitoyltransferase 1 antibody, Serine palmitoyltransferase 1 antibody, serine palmitoyltransferase long chain base subunit 1 antibody, serine palmitoyltransferase, long chain base subunit 1 antibody, serine palmitoyltransferase, long chain base subunit 1 L homeolog antibody, SPT1 antibody, AFUA_6G00300 antibody, PAS_FragB_0040 antibody, SPTLC1 antibody, sptlc1 antibody, sptlc1.L antibody, Sptlc1 antibody

Background: This gene encodes a member of the class-II pyridoxal-phosphate-dependent aminotransferase family. The encoded protein is the long chain base subunit 1 of serine palmitoyltransferase. Serine palmitoyltransferase converts L-serine and palmitoyl-CoA to 3-oxosphinganine with pyridoxal 5'-phosphate and is the key enzyme in sphingolipid biosynthesis. Mutations in this gene were identified in patients with hereditary sensory neuropathy type 1. Alternatively spliced variants encoding different isoforms have been identified. Pseudogenes of this gene have been defined on chromosomes 1, 6, 10, and 13.,SPTLC1,HSAN1,HSN1,LBC1,LCB1,SPT1,SPTI,Cancer,Signal Transduction,Endocrine & Metabolism,Lipid Metabolism,Cholesterol Metabolism,Neuroscience,Neurodegenerative Diseases,Cardiovascular,Lipids,SPTLC1

Molecular Weight: 16 kDa/52 kDa

Gene ID: 10558

UniProt: O15269