SUCLA2 antibody (AA 1-180)

Catalog No. ABIN6148688

Product Details anti-SUCLA2 Antibody

Target: SUCLA2 (Succinate-CoA Ligase, ADP-Forming, beta Subunit (SUCLA2))

Binding Specificity: AA 1-180

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SUCLA2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: MAASMFYGRL VAVATLRNHR PRTAQRAAAQ VLGSSGLFNN HGLQVQQQQQ RNLSLHEYMS MELLQEAGVS VPKGYVAKSP DEAYAIAKKL GSKDVVIKAQ VLAGGRGKGT FESGLKGGVK IVFSPEEAKA VSSQMIGKKL FTKQTGEKGR ICNQVLVCER KYPRREYYFA ITMERSFQGP

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-180 of human SUCLA2 (NP_003841.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:1000

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for SUCLA2

Target: SUCLA2 (Succinate-CoA Ligase, ADP-Forming, beta Subunit (SUCLA2))

Alternative Name: SUCLA2 (SUCLA2 Products)

Synonyms: 4930547K18Rik antibody, A-BETA antibody, MTDPS5 antibody, SCS-betaA antibody, SCS antibody, succinate-Coenzyme A ligase, ADP-forming, beta subunit antibody, succinate-CoA ligase ADP-forming beta subunit antibody, Sucla2 antibody, SUCLA2 antibody

Background: Succinyl-CoA synthetase (SCS) is a mitochondrial matrix enzyme that acts as a heterodimer, being composed of an invariant alpha subunit and a substrate-specific beta subunit. The protein encoded by this gene is an ATP-specific SCS beta subunit that dimerizes with the SCS alpha subunit to form SCS-A, an essential component of the tricarboxylic acid cycle. SCS-A hydrolyzes ATP to convert succinate to succinyl-CoA. Defects in this gene are a cause of myopathic mitochondrial DNA depletion syndrome. A pseudogene of this gene has been found on chromosome 6.,SUCLA2,A-BETA,A-SCS,MTDPS5,SCS-betaA,Signal Transduction,Endocrine & Metabolism,Mitochondrial metabolism,Mitochondrial markers,Neuroscience,Cardiovascular,Heart,Cardiac metabolism,SUCLA2

Molecular Weight: 48 kDa/50 kDa

Gene ID: 8803

UniProt: Q9P2R7