TLE1 antibody (AA 501-770)

Catalog No. ABIN6149205

Product Details anti-TLE1 Antibody

Target: TLE1 (Transducin-Like Enhancer of Split 1 (E(sp1) Homolog, Drosophila) (TLE1))

Binding Specificity: AA 501-770

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TLE1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: TGGKGCVKVW DISHPGNKSP VSQLDCLNRD NYIRSCKLLP DGCTLIVGGE ASTLSIWDLA APTPRIKAEL TSSAPACYAL AISPDSKVCF SCCSDGNIAV WDLHNQTLVR QFQGHTDGAS CIDISNDGTK LWTGGLDNTV RSWDLREGRQ LQQHDFTSQI FSLGYCPTGE WLAVGMESSN VEVLHVNKPD KYQLHLHESC VLSLKFAYCG KWFVSTGKDN LLNAWRTPYG ASIFQSKESS SVLSCDISVD DKYIVTGSGD KKATVYEVIY

Cross-Reactivity: Human

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 501-770 of human TLE1 (NP_005068.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for TLE1

Target: TLE1 (Transducin-Like Enhancer of Split 1 (E(sp1) Homolog, Drosophila) (TLE1))

Alternative Name: TLE1 (TLE1 Products)

Synonyms: ESG antibody, ESG1 antibody, GRG1 antibody, C230057C06Rik antibody, Estm14 antibody, Grg1 antibody, Tle4l antibody, TLE1 antibody, transducin like enhancer of split 1 antibody, transducin-like enhancer protein 1 antibody, transducin-like enhancer of split 1 antibody, transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) antibody, TLE1 antibody, Smp_150080 antibody, Tle1 antibody, LOC100354911 antibody, LOC100524475 antibody, LOC100061341 antibody

Background: Transcriptional corepressor that binds to a number of transcription factors. Inhibits NF-kappa-B-regulated gene expression. Inhibits the transcriptional activation mediated by FOXA2, and by CTNNB1 and TCF family members in Wnt signaling. Enhances FOXG1/BF-1- and HES1-mediated transcriptional repression (By similarity. The effects of full-length TLE family members may be modulated by association with dominant-negative AES. Unusual function as coactivator for ESRRG.,TLE1,ESG,ESG1,GRG1,Epigenetics & Nuclear Signaling,Cell Biology & Developmental Biology,Wnt/β-Catenin Signaling Pathway,Stem Cells,TLE1

Molecular Weight: 83 kDa

Gene ID: 7088

UniProt: Q04724

Pathways: WNT Signaling, SARS-CoV-2 Protein Interactome