UBTF antibody (AA 200-440)

Catalog No. ABIN6149866

Product Details anti-UBTF Antibody

Target: UBTF (Upstream Binding Transcription Factor, RNA Polymerase I (UBTF))

Binding Specificity: AA 200-440

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UBTF antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: KTPQQLWYTH EKKVYLKVRP DATTKEVKDS LGKQWSQLSD KKRLKWIHKA LEQRKEYEEI MRDYIQKHPE LNISEEGITK STLTKAERQL KDKFDGRPTK PPPNSYSLYC AELMANMKDV PSTERMVLCS QQWKLLSQKE KDAYHKKCDQ KKKDYEVELL RFLESLPEEE QQRVLGEEKM LNINKKQATS PASKKPAQEG GKGGSEKPKR PVSAMFIFSE EKRRQLQEER PELSESELTR L

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 200-440 of human UBTF (NP_055048.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for UBTF

Target: UBTF (Upstream Binding Transcription Factor, RNA Polymerase I (UBTF))

Alternative Name: UBTF (UBTF Products)

Synonyms: NOR-90 antibody, UBF antibody, UBF-1 antibody, UBF1 antibody, A930005G04Rik antibody, Tcfubf antibody, wu:fj38c10 antibody, si:dz180g5.3 antibody, ubf antibody, Ubtf antibody, ubf1 antibody, xUBF antibody, xUBFbeta2 antibody, UBTF antibody, nor-90 antibody, ubf2 antibody, ubtf antibody, upstream binding transcription factor, RNA polymerase I antibody, upstream binding transcription factor, RNA polymerase I L homeolog antibody, upstream binding transcription factor, RNA polymerase I S homeolog antibody, UBTF antibody, Ubtf antibody, ubtf antibody, ubtf.L antibody, ubtf.S antibody

Background: This gene encodes a member of the HMG-box DNA-binding protein family. The encoded protein plays a critical role in ribosomal RNA transcription as a key component of the pre-initiation complex, mediating the recruitment of RNA polymerase I to rDNA promoter regions. The encoded protein may also play important roles in chromatin remodeling and pre-rRNA processing, and its activity is regulated by both phosphorylation and acetylation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Pseudogenes of this gene are located on the short arm of chromosomes 3, 11 and X and the long arm of chromosome 11.,UBTF,NOR-90,UBF,UBF-1,UBF1,UBF2,Epigenetics & Nuclear Signaling,Transcription Factors,Signal Transduction,MAPK-Erk Signaling Pathway,UBTF

Molecular Weight: 84 kDa/89 kDa

Gene ID: 7343

UniProt: P17480