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CD7 antibody (PE)

CD7 Reactivity: Human FACS Host: Mouse Monoclonal MEM-186 PE

Catalog No. ABIN616789

Datasheet as PDF

Target See all CD7 Antibodies

CD7
Reactivity
180

25

10

10

7
Human
Host
95

85

1

1
Mouse
Compatible Secondaries
Clonality
98

83

1
Monoclonal
Conjugate
65

18

15

13

9

8

3

3

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
This CD7 antibody is conjugated to PE
Application
105

67

51

28

22

15

12

12

7

5

3

2

1

1

1

1
Flow Cytometry (FACS)

Specificity

This antibody reacts with CD7, a 40 kDa type I transmembrane glycoprotein expressed on peripheral blood T lymphocytes, NK-cells, hematopoietic progenitors, monocytes (weakly) and also on acute lymphocytic leukemia.

Cross-Reactivity (Details)

Species reactivity (tested):Human

Clone

MEM-186

Isotype

IgG1

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anti-CD7 (CD7) (AA 26-180) antibody
CD7 Reactivity: Human FACS, WB, ELISA, IHC Host: Mouse Monoclonal 3D11F12 unconjugated

anti-CD7 (CD7) antibody
CD7 Reactivity: Human FACS, WB, IP, IHC (p) Host: Mouse Monoclonal MEM-186 unconjugated

anti-CD7 (CD7) (AA 26-180) antibody
CD7 Reactivity: Human FACS, WB, ELISA Host: Mouse Monoclonal 2B1C9 unconjugated

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CD7 Reactivity: Human FACS, WB, ELISA, IHC Host: Mouse Monoclonal 5B10E3 unconjugated

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CD7 Reactivity: Human WB, IHC Host: Rabbit Monoclonal unconjugated

anti-CD7 (CD7) (AA 24-150) antibody
CD7 Reactivity: Mouse WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated

anti-CD7 (CD7) (AA 21-240) antibody
CD7 Reactivity: Human WB, ELISA, IP Host: Mouse Monoclonal 1B8 unconjugated

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CD7 Reactivity: Human IHC Host: Rabbit Monoclonal MSVA-007R unconjugated Recombinant Antibody

Application Notes

Optimal working dilution should be determined by the investigator.

Restrictions

For Research Use only
Buffer

Phosphate buffered saline (PBS) containing 15 mM sodium azide and 0.2 % (w/v) high-grade protease free Bovine Serum Albumin (BSA) as a stabilizing agent.

Preservative

Sodium azide

Precaution of Use

This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Target

CD7

Alternative Name

CD7 (CD7 Products)

Synonyms

GP40 antibody, LEU-9 antibody, TP41 antibody, Tp40 antibody, CD7 molecule antibody, CD7 antigen antibody, Cd7 molecule antibody, CD7 antibody, Cd7 antibody

Background

CD7, also known as gp40, is a member of the immunoglobulin superfamily found on T cells, NK cells, thymocytes, hematopoietic progenitors, and monocytes (weakly). CD7 is also expressed on acute lymphocytic leukemia (ALL). CD7 crosslinking induces a calcium flux in T lymphocytes, presumably as a result of cytoplasmic domain association with PI3-kinase. CD7 co-stimulation can induce cytokine secretion and modulate cellular adhesion. A ligand of CD7, epithelial cell secreted protein K12, is produced in thymus to regulate thymocyte signaling and cytokine release. In lung microvascular endothelial cells CD7 serves as an IgM Fc receptor. Expression of CD7 is an important marker used in leukemia diagnostics.Synonyms: GP40, Leu-9, T-cell leukemia antigen, TP41

Gene ID

924

Pathways

Cell-Cell Junction Organization