MMP2 antibody (AA 444-575)
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- Target See all MMP2 Antibodies
- MMP2 (Matrix Metalloproteinase 2 (MMP2))
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Binding Specificity
- AA 444-575
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This MMP2 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)
- Purpose
- Mouse Monoclonal anti-MMP2 / Collagenase-Type-IV-A (MMP2/1501), Purified, BSA-free
- Characteristics
- This antibody recognizes a protein of 72 kDa, which is identified as MMP2. The matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components, including collagen, gelatin, Fibronectin, Laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester, lipopolysaccharide (LPS) or staphylococcal enterotoxin B (SEB). MMP catalysis requires both calcium and zinc. MMP-2 (also designated type IV collagenase) cleaves collagen types IV,V, VII and X and gelatin type I. Activation of MMP-2 secretion requires the Ras signaling pathway. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
- Purification
- Purified
- Immunogen
- Recombinant human MMP2 protein fragment (aa444-575) (exact sequence is proprietary)
- Clone
- MMP2-1501
- Isotype
- IgG1
- Top Product
- Discover our top product MMP2 Primary Antibody
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- Application Notes
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Immunofluorescence 0.5-1 μg/mL
- Flow Cytometry 0.5-1 μg/million cells/0.1 mL
- Western blotting 0.5-1 μg/mL
- Optimal dilution for a specific application should be determined by user
- Comment
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U-138 MG or U-87 MG cells. Placenta
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS (no BSA, no azide)
- Preservative
- Azide free
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- Target
- MMP2 (Matrix Metalloproteinase 2 (MMP2))
- Alternative Name
- MMP2 / Collagenase-Type-IV-A (MMP2 Products)
- Synonyms
- 2-MMP antibody, CG1794 antibody, DM2-MMP antibody, Dm2-MMP antibody, Dmel\\CG1794 antibody, MMP2 antibody, anon-WO0118547.84 antibody, dm-2MMP antibody, dmmp2 antibody, l(2)02353 antibody, mmp2 antibody, wu:fa99h12 antibody, wu:fk89d01 antibody, fgmmp-2 antibody, Mmp-2 antibody, LOC100135793 antibody, Clg4a antibody, GelA antibody, MMP-2 antibody, CLG4 antibody, CLG4A antibody, MMP-II antibody, MONA antibody, TBE-1 antibody, matrix metallopeptidase 2 antibody, Matrix metalloproteinase 2 antibody, matrix metalloproteinase 2 antibody, matrix metalloproteinase-2 antibody, MMP2 antibody, Mmp2 antibody, mmp2 antibody, LOC657982 antibody, LOC100135793 antibody
- Background
- 72 kD type IV collagenase|CLG4A|Collagenase Type 4 alpha|Collagenase type IV A|Gelatinase A|Gelatinase alpha|Gelatinase neutrophil|Matrix metalloproteinase-2|MMP2|MONA|Neutrophil gelatinase|PEX|TBE-1
- Molecular Weight
- 72 kDa (Pro), 63 kDa (cleaved)
- Gene ID
- 4313, 513617
- UniProt
- P08253
- Pathways
- Activation of Innate immune Response
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